4-(2-fluorobenzyloxy)-3-chlorobenzenamine - Names and Identifiers
4-(2-fluorobenzyloxy)-3-chlorobenzenamine - Physico-chemical Properties
Molecular Formula | C13H11ClFNO
|
Molar Mass | 251.68 |
Density | 1.306±0.06 g/cm3(Predicted) |
Boling Point | 390.5±32.0 °C(Predicted) |
pKa | 3.95±0.10(Predicted) |
4-(2-fluorobenzyloxy)-3-chlorobenzenamine - Introduction
Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is an organic compound with the chemical formula C13H11ClFNO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
1. Appearance: Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is colorless or light yellow crystal.
2. Melting Point: its melting point range is 90-92 ° C.
3. Solubility: It is soluble in organic solvents such as acetone, chloroform and dimethylformamide at room temperature.
Use:
The main use of Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is as an intermediate in organic synthesis. It can be used in the synthesis of fluorescent dyes, pharmaceutical preparations and pesticides and other compounds.
Method:
A commonly used preparation method is to obtain Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-through the substitution reaction of p-chloroaniline-. The specific steps are first reacting chloroaniline with 2-fluorobenzyl alcohol, and adding a cuprous chloride catalyst. After completion of the reaction, the product was purified by the steps of crystallization, filtration, and washing.
Safety Information:
1. Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-General laboratory safety procedures should be followed during handling and storage, including wearing protective glasses and gloves.
2. It is a toxic compound, avoid contact with the skin and inhalation of its vapors. Adequate ventilation shall be provided during handling.
3. If taken by mistake or inhaled, consult a doctor immediately and provide details of the compound.
Last Update:2024-04-09 02:00:43