4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline

4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline - Names and Identifiers

Name	Hydroxychloroquine Impurity F
Synonyms	NX-357 Plaquenil Impurity 2 Chloroquine Impurity A Hydroxychloroquine Impurity F Hydroxychloroquine sulfate Impurity F 4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline 7-Chloro-4-(2-methylpyrrolidin-1-yl)quinoline 7-Chloro-4-(2-methyl-1-pyrrolidinyl)quinoline
CAS	6281-58-9

4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline - Physico-chemical Properties

Molecular Formula	C14H15ClN2
Molar Mass	246.74
Density	1.214±0.06 g/cm3(Predicted)
Boling Point	141-147 °C(Press: 0.02 Torr)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Oil
Color	Yellow to Light Brown
pKa	7.70±0.50(Predicted)
Storage Condition	Refrigerator
MDL	MFCD01685619

4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline - Risk and Safety

Toxicity

LD50 intravenous in mouse: 56mg/kg

4-(2-methyl-1-pyrrolidyl)-7-chloroquinoline - Reference Information

biological activity

Hydroxychloroquine impure F is an Impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent that also inhibits Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine effectively inhibited infection by SARS-CoV-2.

Last Update：2024-04-09 21:54:55