4-(3,4-Difluorophenoxy)aniline - Names and Identifiers
4-(3,4-Difluorophenoxy)aniline - Physico-chemical Properties
Molecular Formula | C12H9F2NO
|
Molar Mass | 221.2 |
Density | 1.295±0.06 g/cm3(Predicted) |
Boling Point | 316.1±42.0 °C(Predicted) |
pKa | 4.69±0.10(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD02663360 |
4-(3,4-Difluorophenoxy)aniline - Risk and Safety
Hazard Symbols | Xi - Irritant

|
Hazard Class | IRRITANT |
4-(3,4-Difluorophenoxy)aniline - Introduction
4-(3,4-Difluorophenoxy)aniline is an organic compound with the chemical formula C12H9F2NO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Melting point: 85-87°C
-Boiling point: 373.5°C
-Density: 1.315g/cm³
Use:
4-(3,4-Difluorophenoxy)aniline has many uses in organic synthesis, mainly for the preparation of other compounds. It can be used as a precursor for organic dyes and can be used to synthesize chemicals such as pigments, dyes and coatings. In addition, it can also be used as a pharmaceutical intermediate for the synthesis of drugs, pesticides and other biologically active molecules.
Preparation Method:
4-(3,4-Difluorophenoxy)aniline can be prepared by the following steps:
1. first, 3,4-difluorophenol and aniline react in the presence of alkali to generate N-(phenyl) 3,4-difluoroaniline.
2. Then, under the catalysis of acid, N-(phenyl) 3,4-difluoroaniline reacts with phenol to generate 4-(3,4-Difluorophenoxy)aniline.
Safety Information:
4-(3,4-Difluorophenoxy)aniline is a chemical that needs to be safe when used.
-It may be irritating and corrosive to the skin, eyes and respiratory system, so wear appropriate personal protective equipment such as gloves, goggles and protective masks when handling.
-Avoid inhaling dust, fumes or mist, and make sure to operate in a well-ventilated area.
-It should be stored in a dry, cool place, away from fire and oxidizing agents.
-When using or disposing, please handle in accordance with local laws and regulations, and follow relevant safety operation procedures and recommendations.
Last Update:2024-04-09 20:49:11