4-(3,5-二甲氧基苯基)哌嗪-1-羧酸叔丁酯
tert-Butyl 4-(3,5-dimethoxyphenyl)piperazine-1-carboxylate
CAS: 1121596-71-1
Molecular Formula: C17H26N2O4
4-(3,5-二甲氧基苯基)哌嗪-1-羧酸叔丁酯 - Names and Identifiers
4-(3,5-二甲氧基苯基)哌嗪-1-羧酸叔丁酯 - Physico-chemical Properties
| Molecular Formula | C17H26N2O4 |
| Molar Mass | 322.4 |
| Density | 1.119±0.06 g/cm3(Predicted) |
| Boling Point | 458.4±45.0 °C(Predicted) |
| pKa | 2.45±0.20(Predicted) |
4-(3,5-二甲氧基苯基)哌嗪-1-羧酸叔丁酯 - Introduction
1-(3,5-Dimethoxyphenyl)-4-Boc-piperazine is an organic compound with the following properties, uses, preparation and safety information:
Nature:
-Chemical formula: C17H24N2O3
-Appearance: White crystalline solid
-Melting point: about 95-97°C
-Solubility: Soluble in organic solvents such as dichloromethane, ether and methanol
Use:
- 1-(3,5-dimethoxyphenyl)-4-Boc-piperazine is a commonly used intermediate, which can be used in a variety of reactions in organic synthesis. It can be used as a starting material or intermediate for the synthesis of other organic compounds, such as biologically active compounds and drugs.
Preparation Method:
The preparation of 1-(3,5-dimethoxyphenyl)-4-Boc-piperazine can be carried out by the following steps:
-Step 1: 4-azadimethylchloroformate reacts with 3,5-dimethoxyaniline under basic conditions to generate 4-azadimethylperoate.
-Step 2: React 4-azadimethylperoate with chloropropyldimethylamine to generate 1-(3,5-dimethoxyphenyl)-4-azadimethylperoyl Amine.
-Step 3: 1-(3,5-dimethoxyphenyl)-4-azadimethylperoxylamine is reacted with Boc acid chloride to generate 1-(3,5-dimethoxyphenyl)-4-Boc-piperazine.
Safety Information:
- 1-(3,5-Dimethoxyphenyl)-4-Boc-piperazine is generally stable and safe to handle under normal operating conditions.
-Avoid contact with skin and eyes while maintaining a well-ventilated laboratory environment.
-Care should be taken to prevent inhalation, ingestion or swallowing of the compound, and appropriate personal protective measures such as gloves, goggles and gas masks are necessary.
-If inhaled or exposed to the compound, rinse the affected area immediately with water and seek medical advice immediately.
Nature:
-Chemical formula: C17H24N2O3
-Appearance: White crystalline solid
-Melting point: about 95-97°C
-Solubility: Soluble in organic solvents such as dichloromethane, ether and methanol
Use:
- 1-(3,5-dimethoxyphenyl)-4-Boc-piperazine is a commonly used intermediate, which can be used in a variety of reactions in organic synthesis. It can be used as a starting material or intermediate for the synthesis of other organic compounds, such as biologically active compounds and drugs.
Preparation Method:
The preparation of 1-(3,5-dimethoxyphenyl)-4-Boc-piperazine can be carried out by the following steps:
-Step 1: 4-azadimethylchloroformate reacts with 3,5-dimethoxyaniline under basic conditions to generate 4-azadimethylperoate.
-Step 2: React 4-azadimethylperoate with chloropropyldimethylamine to generate 1-(3,5-dimethoxyphenyl)-4-azadimethylperoyl Amine.
-Step 3: 1-(3,5-dimethoxyphenyl)-4-azadimethylperoxylamine is reacted with Boc acid chloride to generate 1-(3,5-dimethoxyphenyl)-4-Boc-piperazine.
Safety Information:
- 1-(3,5-Dimethoxyphenyl)-4-Boc-piperazine is generally stable and safe to handle under normal operating conditions.
-Avoid contact with skin and eyes while maintaining a well-ventilated laboratory environment.
-Care should be taken to prevent inhalation, ingestion or swallowing of the compound, and appropriate personal protective measures such as gloves, goggles and gas masks are necessary.
-If inhaled or exposed to the compound, rinse the affected area immediately with water and seek medical advice immediately.
Last Update：2024-04-09 19:05:44
