4-(3-(Isopropylamino)-2-hydroxypropoxy)indole
Pindolol
CAS: 13523-86-9
Molecular Formula: C14H20N2O2
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Names and Identifiers
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Physico-chemical Properties
| Molecular Formula | C14H20N2O2 |
| Molar Mass | 248.32 |
| Density | 1.0606 (rough estimate) |
| Melting Point | 167-171°C(lit.) |
| Boling Point | 391.39°C (rough estimate) |
| Flash Point | 230.3°C |
| Water Solubility | 33mg/L(22.5 ºC) |
| Solubility | 0.1 M NaOH: 0.2mg/mL |
| Vapor Presure | 3.77E-09mmHg at 25°C |
| Appearance | powder |
| Color | white to off-white |
| Merck | 13,7525 |
| pKa | pKa 9.26 (Uncertain) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5110 (estimate) |
| Physical and Chemical Properties | White or off-white crystalline powder. Melting point 171-173 ℃, soluble in acetic acid, slightly soluble in methanol, insoluble in water, benzene. |
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 3249 |
| WGK Germany | 3 |
| RTECS | UB6660000 |
| HS Code | 2933995300 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 oral in rabbit: 650mg/kg |
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Standard
Authoritative Data Verified Data
This product is 3-(isopropylaminoindol-4-oxy)-2-propanol. Calculated as dried product, including C14H20N202 shall not be less than 99.0%.
Last Update：2024-01-02 23:10:35
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Trait
Authoritative Data Verified Data
- This product is white or off-white crystalline powder; Slightly abnormal odor.
- This product is slightly soluble in methanol or ethanol, almost insoluble in water or benzene; Soluble in glacial acetic acid.
melting point
The melting point of this product (General 0612) is 167~171°C.
Last Update：2022-01-01 11:57:24
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Differential diagnosis
Authoritative Data Verified Data
- take this product, add anhydrous ethanol to dissolve and make a solution containing about 10ug per lml, and measure by UV-Vis spectrophotometry (General rule 0401), there is maximum absorption at wavelengths of 265nm and 288nm.
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 610).
Last Update：2022-01-01 11:57:25
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Exam
Authoritative Data Verified Data
loss on drying
take this product, dry to constant weight at 105°C, weight loss shall not exceed 0.5% (General rule 0831).
ignition residue
take l.Og of this product and check it according to law (General rule 0841). The residue left shall not exceed 0.1%.
Heavy metals
The residue left under the item of taking the ignition residue shall not contain more than 10 parts per million of heavy metal when examined by law (General Principles 0821, Law II).
Last Update：2022-01-01 11:57:25
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Content determination
Authoritative Data Verified Data
take about 0.lg of this product, precision weighing, add 10ml of glacial acetic acid to dissolve, add 1 drop of crystal violet indicator solution, and use perchloric acid titration solution (0.1 mol/L) titration to a blue color of the solution, and the results of the titration were corrected by a blank test. Each 1 ml of perchloric acid titration solution (0.1 mol/L) corresponds to 24.83mg of C14H20N202.
Last Update：2022-01-01 11:57:25
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Category
Authoritative Data Verified Data
B adrenergic receptor blockers.
Last Update：2022-01-01 11:57:26
4-(3-(Isopropylamino)-2-hydroxypropoxy)indole - Storage
Authoritative Data Verified Data
light shielding, sealed storage.
Last Update：2022-01-01 11:57:26
