4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)-isoxazol-5(4H)-one
CAS: 1142198-92-2
Molecular Formula: C11H7Cl2NO2
4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one - Names and Identifiers
4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one - Physico-chemical Properties
| Molecular Formula | C11H7Cl2NO2 |
| Molar Mass | 256.08 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12027780 |
4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one - Risk and Safety
| Hazard Class | IRRITANT |
4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one - Introduction
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)-isoxazol-5(4H)-one, also known as (4E)-4-(3-chlorobenzylmethylene)-3-(chloromethyl)-isoxazol-5(4H)-one. The following is a description of its nature, use, formulation and safety information:
Nature:
-Chemical formula: C14H10Cl2N2O2
-Molecular weight: 313.14g/mol
-Appearance: Colorless to light yellow crystal
-Melting point: 159-160°C
-Solubility: Soluble in organic solvents such as chloroform and dimethyl sulfoxide, slightly soluble in ethanol and ether.
Use:
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)-isoxazol-5(4H)-one can be used:
-As an intermediate in organic synthesis, used in the synthesis of other organic compounds.
-in the field of medicine, may have antibacterial, anti-inflammatory, anti-tumor and other pharmacological activities.
Preparation Method:
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)-isoxazol-5(4H)-one can be synthesized by the following method:
an appropriate amount of 3-chlorobenzaldehyde and ethyl chloroacetate are heated to react under alkaline conditions to generate (4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one.
The desired product is then purified by crystallization or chromatography.
Safety Information:
Nature:
-Chemical formula: C14H10Cl2N2O2
-Molecular weight: 313.14g/mol
-Appearance: Colorless to light yellow crystal
-Melting point: 159-160°C
-Solubility: Soluble in organic solvents such as chloroform and dimethyl sulfoxide, slightly soluble in ethanol and ether.
Use:
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)-isoxazol-5(4H)-one can be used:
-As an intermediate in organic synthesis, used in the synthesis of other organic compounds.
-in the field of medicine, may have antibacterial, anti-inflammatory, anti-tumor and other pharmacological activities.
Preparation Method:
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)-isoxazol-5(4H)-one can be synthesized by the following method:
an appropriate amount of 3-chlorobenzaldehyde and ethyl chloroacetate are heated to react under alkaline conditions to generate (4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one.
The desired product is then purified by crystallization or chromatography.
Safety Information:
Last Update：2024-04-09 02:00:56
