4-(3-Fluorobenzyloxy)-3-chloronitrobenzene

4-(3-Fluorobenzyloxy)-3-chloronitrobenzene - Names and Identifiers

Name	3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene
Synonyms	Lapatinib genotoxic impurity 2 2-Chloro-1-(3-fluoro-benzyloxy)-4-nitro- 4-(3-Fluorobenzyloxy)-3-chloronitrobenzene 3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene 1-(3-fluorobenzyloxy)-2-chloro-4-nitrobenzene 2-Chloro-1-(3-fluoro-benzyloxy)-4-nitrobenzene 2-Chloro-1-(3-fluoro-benzyloxy)-4-nitro-benzene 1-Fluoro-3-[(4-nitro-2-chlorophenoxy)Methyl]benzene Benzene,2-chloro-1-[(3-fluorophenyl)Methoxy]-4-nitro-
CAS	443882-99-3
InChI	InChI=1/C13H9ClFNO3/c14-12-7-11(16(17)18)4-5-13(12)19-8-9-2-1-3-10(15)6-9/h1-7H,8H2
InChIKey	SFTHVDYRPHJAND-UHFFFAOYSA-N

4-(3-Fluorobenzyloxy)-3-chloronitrobenzene - Physico-chemical Properties

Molecular Formula	C13H9ClFNO3
Molar Mass	281.67
Density	1.393±0.06 g/cm3(Predicted)
Melting Point	99.0 to 103.0 °C
Boling Point	400.5±35.0 °C(Predicted)
Flash Point	196°C
Vapor Presure	2.92E-06mmHg at 25°C
Appearance	powder to crystal
Color	White to Light yellow
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.596

4-(3-Fluorobenzyloxy)-3-chloronitrobenzene - Introduction

3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene is an organic compound whose chemical formula is C13H8ClFNO3.

Nature:
-Appearance: 3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene is a white crystalline solid.
-Melting point: about 85-87°C.
-Boiling point: about 394-396°C.
-Density: about 1.39g/cm³.
-Solubility: Almost insoluble in water, but soluble in organic solvents such as dimethyl sulfoxide and dichloromethane.

Use:
3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene is commonly used as an intermediate in organic synthesis and is used to prepare other organic compounds. It can be used to synthesize new acid dyes, fluorescent dyes and so on. In addition, it can also be used in chemical research in the field of medicine.

Preparation Method:
3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene are generally synthesized by the following steps:
1. 3-chloronitrobenzene reacts with 3-fluorobenzyl alcohol to generate 3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene.

Safety Information:
3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene is a kind of organic matter, generally has certain toxicity. Wear appropriate personal protective equipment such as chemical protective goggles, chemical protective gloves and protective face masks when handling or using. Keep away from ignition sources and avoid contact with strong oxidants. During storage, it should be kept in a dry, well-ventilated place, away from fire and combustibles. If an accident occurs, you should immediately take corresponding measures to protect your own safety and immediately seek help from professionals. When handling or disposing of the compound, the relevant regulations and safe operating procedures should be observed.

Last Update：2024-04-09 02:00:46