4-(3H-benzimidazol-5-yloxy)aniline

4-(3H-benzimidazol-5-yloxy)aniline - Names and Identifiers

Name	Benzenamine, 4-(1H-benzimidazol-6-yloxy)-
Synonyms	4-(3H-benzimidazol-5-yloxy)aniline 4-(1H-Benzimidazol-6-yloxy)aniline 4-(1H-benzimidazol-6-yloxy)Benzenamine 4-(1H-Benzimidazol-6-yloxy)-benzenamine 4-((1H-Benzo[d]iMidazol-6-yl)oxy)aniline BenzenaMine, 4-(1H-benziMidazol-6-yloxy)- Benzenamine, 4-(1H-benzimidazol-6-yloxy)-
CAS	317830-22-1

4-(3H-benzimidazol-5-yloxy)aniline - Physico-chemical Properties

Molecular Formula	C13H11N3O
Molar Mass	225.25
Storage Condition	2-8°C

4-(3H-benzimidazol-5-yloxy)aniline - Introduction

Benzenamine, 4-is an organic compound with the chemical formula C13H12N4O.

Its properties are as follows:

Appearance: White to light yellow crystalline powder
Melting point: about 240-245 ° C
Solubility: Soluble in acidic and alkaline solutions, insoluble in water and organic solvents.

Benzenamine, 4-(Ti)-is mainly used as an intermediate for antitumor drugs and antiviral drugs. It has antitumor and antiviral activities and can be used to synthesize highly effective anticancer and antiviral drugs.

The method of preparing Benzenamine, 4-(Ti)-usually involves the following steps:
1. 1-Aminoacetophenone and dimethyl sulfoxide are subjected to a condensation reaction under alkaline conditions to obtain 1-(2-dimethylsulfoxide) acetophenone.
2. Subsequently, 1-(2-dimethylsulfoxide) acetophenone and 1,6-dicyanohexane are reacted under basic conditions to give 4-(1H-benzimidazole-6-oxy) acetophenone.
3.4-(1H-benzimidazole-6-oxy) acetophenone was reduced to Benzenamine, 4-(quinyl)-by hydrogenation or by direct amination in the presence of barium-water-.

For safety information, note the following:
1. Avoid inhalation, ingestion or contact with skin, eyes and mucous membranes.
2. In case of accidental contact, please rinse with plenty of water or saline for at least 15 minutes, and seek medical help.
3. Please wear appropriate protective gloves and glasses when using.
4. Storage should be sealed, away from the fire and oxidant.

This information is based on general information. For specific situations and uses, it is recommended to refer to the relevant literature or consult a chemical professional.

Last Update：2024-04-09 18:58:34