4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole - Names and Identifiers

Name	Indole-4-boronic acid pinacol ester
Synonyms	Indole-4-boronic acid pin... 1H-indol-4-ylboronic acid pinacol Indole-4-boronic acid pinacol ester 1H-Indole-4-boronic acid, pinacol ester 4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 1H-Indole,4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole, 2-(1H-Indol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS	388116-27-6
InChI	InChI=1/C14H18BNO2/c1-13(2)14(3,4)18-15(17-13)11-6-5-7-12-10(11)8-9-16-12/h5-9,16H,1-4H3
InChIKey	QDCIXBBEUHMLDN-UHFFFAOYSA-N

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole - Physico-chemical Properties

Molecular Formula	C14H18BNO2
Molar Mass	243.11
Density	1.11±0.1 g/cm3(Predicted)
Melting Point	120-125°C(lit.)
Boling Point	396.0±15.0 °C(Predicted)
Flash Point	193.3°C
Vapor Presure	4.03E-06mmHg at 25°C
pKa	16.83±0.30(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.562

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole - Introduction

Indole-4-boronic acid pinacol ester is an organic compound with the chemical formula C15H19BO2, it is a white solid.

The compound is commonly used as a boron reagent in metal organic chemical reactions. It is a useful reagent that can be developed as a starting point for the preparation of chemical drugs and other organic compounds. It can participate in a series of reactions, including Suzuki coupling reaction, reductive coupling reaction, nucleophilic addition reaction, etc.

The method for preparing Indole-4-boronic acid pinacol ester can be obtained by reacting 4-indole boronic acid and pinacol under appropriate reaction conditions. The specific synthesis method can refer to the literature of organic synthetic chemistry.

Regarding safety information, Indole-4-boronic acid pinacol ester is usually relatively safe under normal use conditions. However, the use of chemicals should follow appropriate practices and safe operating procedures. Avoid contact with skin and eyes, and make sure to operate in a well-ventilated place. If you have any questions or unexpected situations, please consult a professional or refer to the safety data sheet of the chemical.

Last Update：2024-04-09 20:45:29