4-(4-BROMOPHENYL)ACETOPHENONE - Names and Identifiers
4-(4-BROMOPHENYL)ACETOPHENONE - Physico-chemical Properties
Molecular Formula | C14H11BrO
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Molar Mass | 275.14 |
Density | 1.359±0.06 g/cm3(Predicted) |
Melting Point | 129-133°C(lit.) |
Boling Point | 372.1±17.0 °C(Predicted) |
Flash Point | 76.7°C |
Solubility | soluble in Toluene |
Vapor Presure | 9.83E-06mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Orange to Green |
BRN | 2048590 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.592 |
MDL | MFCD00143242 |
4-(4-BROMOPHENYL)ACETOPHENONE - Risk and Safety
Risk Codes | R36 - Irritating to the eyes
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S24/25 - Avoid contact with skin and eyes.
S22 - Do not breathe dust.
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UN IDs | UN 3077 9/PG 3 |
WGK Germany | 3 |
4-(4-BROMOPHENYL)ACETOPHENONE - Introduction
4 '-(4-bromophenyl)acetophenone is an organic compound with the chemical formula C14H11BrO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
4 '-(4-bromophenyl)acetophenone is a solid with white to pale yellow crystals. It has a melting point of about 92-95 degrees Celsius and a boiling point of about 323-325 degrees Celsius. This compound is hardly soluble in water at normal temperature, but soluble in organic solvents such as ether, alcohol and ketone.
Use:
4 '-(4-bromophenyl)acetophenone can be used as an important reagent in organic synthesis, and is often used to synthesize biologically active compounds. It is often used as an intermediate in the synthesis of pharmaceuticals and pesticides. In addition, it can also be used in organic dyes, photosensitive materials and coatings.
Preparation Method:
A common method for preparing 4 '-(4-bromophenyl)acetophenone is by reacting acetophenone with bromobenzene. Specifically, first, acetophenone is reacted with bromobenzene at an appropriate temperature in the presence of a base to produce the target product. Then, the pure product was obtained by crystallization purification.
Safety Information:
When handling 4 '-(4-bromophenyl)acetophenone, you need to pay attention to the following safety precautions:
1. Appropriate personal protective equipment, such as safety glasses, gloves and lab coats, must be worn.
2. Avoid inhaling the dust or gas of the compound. The operation should be carried out in a well-ventilated area, or equipped with personal protective equipment if necessary.
3. Avoid contact with skin and eyes. If exposed to the compound, wash off immediately with plenty of water and seek medical attention immediately.
4. in use and storage, should comply with chemical safety procedures, and keep it away from flammable and explosive materials.
Last Update:2024-04-09 21:01:54