4-(4-BROMOPHENYL)PIPERIDINE
Piperidine, 4-(4-bromophenyl)-
CAS: 80980-89-8
Molecular Formula: C11H14BrN
4-(4-BROMOPHENYL)PIPERIDINE - Names and Identifiers
| Name | Piperidine, 4-(4-bromophenyl)- |
| Synonyms | 4-(4-Bromophenyl)piperidine 4-(4-BROMOPHENYL)PIPERIDINE 4-(4'-bromophenyl)piperidine 4-(4'-BROMOPHENYL)PIPERIDINE Piperidine, 4-(4-bromophenyl)- |
| CAS | 80980-89-8 |
| InChI | InChI=1/C11H14BrN/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10/h1-4,10,13H,5-8H2 |
4-(4-BROMOPHENYL)PIPERIDINE - Physico-chemical Properties
| Molecular Formula | C11H14BrN |
| Molar Mass | 240.14 |
| Density | 1.313±0.06 g/cm3(Predicted) |
| Melting Point | 144-146 °C |
| Boling Point | 307.6±42.0 °C(Predicted) |
| Flash Point | 139.9°C |
| Vapor Presure | 0.000715mmHg at 25°C |
| Appearance | Solid |
| pKa | 10.14±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.553 |
4-(4-BROMOPHENYL)PIPERIDINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R52 - Harmful to aquatic organisms |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
4-(4-BROMOPHENYL)PIPERIDINE - Introduction
Piperidine, 4-(4-bromophenyl)-is an organic compound with the chemical formula C11H14BrN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-melting point: 68-70 ℃
-Boiling Point: No data
-Density: 1.274g/cm3
-Solubility: It has good solubility in some organic solvents, such as ethanol and ether.
Use:
- Piperidine, 4-(4-bromophenyl)-is an important organic synthesis intermediate that can be used to synthesize other compounds.
-It can be used to prepare some drugs, such as analgesics, antiepileptics, etc.
Preparation Method:
- Piperidine, 4-(4-bromophenyl)-can be obtained by a variety of synthetic methods, the following is one of the common preparation methods:
1. First, 4-bromobenzoic acid is reacted with piperidine in an appropriate solvent.
2. The reaction usually requires heating, and the reaction time is longer.
3. Finally, the target product was obtained by crystallization and filtration.
Safety Information:
- Piperidine, 4-(4-bromophenyl)-belongs to organic bromine compounds, bromine contains the risk of mutagenicity and carcinogenicity. Therefore, safe operating procedures must be followed during handling and storage.
-High-purity compounds should have low toxicity. But still follow proper laboratory safety practices, such as wearing gloves and goggles.
-When handling or handling the compound, appropriate ventilation measures should be taken, and contact with the skin and inhalation of its dust should be avoided.
-When using and handling this compound, please refer to the safety data sheet and applicable regulations.
Nature:
-Appearance: Colorless crystalline solid
-melting point: 68-70 ℃
-Boiling Point: No data
-Density: 1.274g/cm3
-Solubility: It has good solubility in some organic solvents, such as ethanol and ether.
Use:
- Piperidine, 4-(4-bromophenyl)-is an important organic synthesis intermediate that can be used to synthesize other compounds.
-It can be used to prepare some drugs, such as analgesics, antiepileptics, etc.
Preparation Method:
- Piperidine, 4-(4-bromophenyl)-can be obtained by a variety of synthetic methods, the following is one of the common preparation methods:
1. First, 4-bromobenzoic acid is reacted with piperidine in an appropriate solvent.
2. The reaction usually requires heating, and the reaction time is longer.
3. Finally, the target product was obtained by crystallization and filtration.
Safety Information:
- Piperidine, 4-(4-bromophenyl)-belongs to organic bromine compounds, bromine contains the risk of mutagenicity and carcinogenicity. Therefore, safe operating procedures must be followed during handling and storage.
-High-purity compounds should have low toxicity. But still follow proper laboratory safety practices, such as wearing gloves and goggles.
-When handling or handling the compound, appropriate ventilation measures should be taken, and contact with the skin and inhalation of its dust should be avoided.
-When using and handling this compound, please refer to the safety data sheet and applicable regulations.
Last Update：2024-04-09 21:01:54
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