4-(AMINOMETHYL)-N-METHYLBENZAMIDE
4-(Aminomethyl)-N-methylbenzamide hydrochloride
CAS: 164648-64-0
Molecular Formula: C9H12N2O
4-(AMINOMETHYL)-N-METHYLBENZAMIDE - Names and Identifiers
4-(AMINOMETHYL)-N-METHYLBENZAMIDE - Physico-chemical Properties
| Molecular Formula | C9H12N2O |
| Molar Mass | 164.2 |
| Density | 1.096±0.06 g/cm3(Predicted) |
| Boling Point | 351.5±25.0 °C(Predicted) |
| pKa | 15.15±0.46(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12027004 |
4-(AMINOMETHYL)-N-METHYLBENZAMIDE - Risk and Safety
| Hazard Class | IRRITANT |
4-(AMINOMETHYL)-N-METHYLBENZAMIDE - Introduction
4-(Aminomethyl)-N-methylbenzamide hydrochloride is an organic compound with the chemical formula C9H12N2O. HCl. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a colorless or slightly yellow solid.
-Solubility: Soluble in water and organic solvents such as methanol or chloroform.
-Melting point: about 160-165°C.
Use:
-Because its molecular structure contains amino and benzene rings, it is often used in organic synthesis as an amine or methylene introduction reagent.
-In addition, it can also be used as an intermediate for the synthesis of drugs and other organic compounds.
Preparation Method:
4-(Aminomethyl)-N-methylbenzamide hydrochloride can be synthesized by the following steps:
1. 4-aminomethylbenzoic acid is obtained by reacting p-tolualdehyde with carbamic anhydride.
2. react 4-amino methyl benzoic acid with formyl chloride to generate 4-(Aminomethyl)-N-methylbenzamide hydrochloride.
3. react it with hydrochloric acid to form 4-(Aminomethyl)-N-methylbenzamide hydrochloride hydrochloride.
Safety Information:
-Wear appropriate personal protective equipment, including eye protection and gloves, during handling and storage.
-Avoid direct contact with skin and inhalation of dust or vapors. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Maintain good ventilation during operation and keep away from flammable materials.
-This compound has not been extensively studied for toxicity and therefore requires careful handling and storage to avoid potential hazards.
Nature:
-Appearance: It is a colorless or slightly yellow solid.
-Solubility: Soluble in water and organic solvents such as methanol or chloroform.
-Melting point: about 160-165°C.
Use:
-Because its molecular structure contains amino and benzene rings, it is often used in organic synthesis as an amine or methylene introduction reagent.
-In addition, it can also be used as an intermediate for the synthesis of drugs and other organic compounds.
Preparation Method:
4-(Aminomethyl)-N-methylbenzamide hydrochloride can be synthesized by the following steps:
1. 4-aminomethylbenzoic acid is obtained by reacting p-tolualdehyde with carbamic anhydride.
2. react 4-amino methyl benzoic acid with formyl chloride to generate 4-(Aminomethyl)-N-methylbenzamide hydrochloride.
3. react it with hydrochloric acid to form 4-(Aminomethyl)-N-methylbenzamide hydrochloride hydrochloride.
Safety Information:
-Wear appropriate personal protective equipment, including eye protection and gloves, during handling and storage.
-Avoid direct contact with skin and inhalation of dust or vapors. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Maintain good ventilation during operation and keep away from flammable materials.
-This compound has not been extensively studied for toxicity and therefore requires careful handling and storage to avoid potential hazards.
Last Update：2024-04-09 21:04:16
