4-(Aminomethyl)tetrahydro-2H-pyran
4-Aminomethyltetrahydropyran
CAS: 130290-79-8
Molecular Formula: C6H13NO
4-(Aminomethyl)tetrahydro-2H-pyran - Names and Identifiers
4-(Aminomethyl)tetrahydro-2H-pyran - Physico-chemical Properties
| Molecular Formula | C6H13NO |
| Molar Mass | 115.17 |
| Density | 1.02 |
| Boling Point | 75 °C |
| Flash Point | 64.9°C |
| Vapor Presure | 0.912mmHg at 25°C |
| pKa | 10.01±0.29(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.4630-1.4670 |
4-(Aminomethyl)tetrahydro-2H-pyran - Risk and Safety
| Risk Codes | R34 - Causes burns R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection. |
| UN IDs | 2735 |
| HS Code | 29329990 |
| Hazard Class | IRRITANT |
| Packing Group | Ⅲ |
4-(Aminomethyl)tetrahydro-2H-pyran - Introduction
4-Methylamine tetrahydropyran is an organic compound with the chemical formula C5H12N2O. It is a colorless liquid with a pungent odor at room temperature. The following is a detailed description of the properties, uses, preparation methods and safety information of 4-methyl amine tetrahydropyran:
Nature:
-Appearance: Colorless liquid.
-Boiling point: about 110°C.
-Density: about 0.92g/cm³.
-Solubility: Soluble in water, alcohols and ether solvents.
Use:
-4-Methylamine tetrahydropyran is commonly used as a solvent in organic synthesis, especially in extraction and ligand chemical reactions.
-It can also be used as a mordant for dyes, an intermediate for fungicides, insecticides and preservatives.
-In the field of medicine, it can be used to synthesize certain drugs.
Preparation Method:
The preparation of 4-methylamine tetrahydropyran usually has many methods, one of which is through the amidation reaction of tetrahydropyran:
1. Add tetrahydropyran to anhydrous acetic acid.
2. Add 1-methylamine to anhydrous acetic acid.
3. Control the reaction temperature to 50-60°C and perform the in-situ amidation reaction.
4. After completion of the reaction, the 4-methylamine tetrahydropyran product was obtained by distillation and purification.
Safety Information:
-4-Methylamine tetrahydropyran has a pungent odor and may cause irritation to the skin, eyes and respiratory tract. Therefore, appropriate personal protective equipment should be worn during use.
-It is a flammable liquid and should be kept away from open flames and high temperature sources.
-During storage and handling, please follow the safe handling procedures for chemicals and follow correct waste disposal methods.
-Before use, please read and understand the safety data sheet (SDS) of the substance.
Nature:
-Appearance: Colorless liquid.
-Boiling point: about 110°C.
-Density: about 0.92g/cm³.
-Solubility: Soluble in water, alcohols and ether solvents.
Use:
-4-Methylamine tetrahydropyran is commonly used as a solvent in organic synthesis, especially in extraction and ligand chemical reactions.
-It can also be used as a mordant for dyes, an intermediate for fungicides, insecticides and preservatives.
-In the field of medicine, it can be used to synthesize certain drugs.
Preparation Method:
The preparation of 4-methylamine tetrahydropyran usually has many methods, one of which is through the amidation reaction of tetrahydropyran:
1. Add tetrahydropyran to anhydrous acetic acid.
2. Add 1-methylamine to anhydrous acetic acid.
3. Control the reaction temperature to 50-60°C and perform the in-situ amidation reaction.
4. After completion of the reaction, the 4-methylamine tetrahydropyran product was obtained by distillation and purification.
Safety Information:
-4-Methylamine tetrahydropyran has a pungent odor and may cause irritation to the skin, eyes and respiratory tract. Therefore, appropriate personal protective equipment should be worn during use.
-It is a flammable liquid and should be kept away from open flames and high temperature sources.
-During storage and handling, please follow the safe handling procedures for chemicals and follow correct waste disposal methods.
-Before use, please read and understand the safety data sheet (SDS) of the substance.
Last Update：2024-04-09 20:48:19
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