4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol - Names and Identifiers

Name	4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol
Synonyms	4-tert-Butyldimethylsilyloxybutanol 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol 1-tert-ButyldiMethylsilyl-4-hydroxybutane 4-[Tert-Butyl(Dimethyl)Silyl]Oxybutan-1-Ol 4-(tert-Butyldimethylsiloxy)butanol300374-99-6 4-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-1-butanol
CAS	87184-99-4

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol - Physico-chemical Properties

Molecular Formula	C10H24O2Si
Molar Mass	204.38
Density	0.888 g/mL at 25 °C (lit.)
Boling Point	63-66 °C/0.3 mmHg (lit.)
Flash Point	222°C
Water Solubility	Slightly Soluble in water.(2.0 g/L) (25°C). Soluble in Dichloromethane, Ethyl Acetate, Methanol
Specific Gravity	0.888
pKa	15.07±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	7: reacts slowly with moisture/water
Refractive Index	n20/D 1.4390(lit.)

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol - Risk and Safety

WGK Germany

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol - Introduction

4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol is an organic compound whose chemical formula is C11H26O2Si. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-relative molecular mass: 214.41g/mol
-Boiling Point: 148-153°C
-Density: 0.89g/cm³
-Refractive Index: 1.452

Use:
- 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol are widely used as reagents and intermediates in chemical synthesis.
-It can be used for different reactions in organic synthesis, such as hydroxylation reaction, substitution reaction and carboxyl reduction reaction in the presence of alcohol.
-Because it contains a silane group, it also has the property of increasing the thermal stability and solubility of the compound.

Preparation Method:
- 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol can be obtained by reacting 4-bromobutanol with sodium tert-butyldimethylsilane.

Safety Information:
- 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol should be stored in a cold, dark place, away from fire and oxidant.
-use should avoid contact with skin, eyes and mucous membranes, avoid inhalation of its vapor.
-Wear appropriate protective gloves, glasses and respiratory protection when used.
-When using or handling the compound, please follow the relevant safety operation guidelines and have the necessary emergency measures and equipment.
-When contacting emergency personnel, please provide safety data and chemical property information for the compound.

Last Update：2024-04-10 22:29:15