Name | N-boc-1,4-phenylene diamine |
Synonyms | N-BOC-P-PHENYLENEDIAMINE N-Boc-p-phenylenediamine BOC-1,4-PHENYLENEDIAMINE N-Boc-benzene-1,4-diaMine N-BOC-1,4-PHENYLENE DIAMINE N-boc-1,4-phenylene diamine 4-(tert-butoxycarbonylamino)aniline tert-butyl (4-aminophenyl)carbamate tert-butyl N-(4-aMinophenyl)carbaMate N-TERT-BUTYLOXYCARBONYL-1,4-PHENYLENEDIAMINE N-tert-Butyloxycarbonyl-1,4-phenylenediamine (4-Amino-phenyl)-carbamic acid tert-butyl ester Carbamicacid,N-(4-aminophenyl)-,1,1-dimethylethylester |
CAS | 71026-66-9 |
EINECS | 275-132-7 |
InChI | InChI=1/C11H16N2O2/c1-11(2,3)15-10(14)13-9-6-4-8(12)5-7-9/h4-7H,12H2,1-3H3,(H,13,14) |
InChIKey | WIVYTYZCVWHWSH-UHFFFAOYSA-N |
Molecular Formula | C11H16N2O2 |
Molar Mass | 208.26 |
Density | 1.152±0.06 g/cm3(Predicted) |
Melting Point | 113-115°C |
Boling Point | 295.4±23.0 °C(Predicted) |
Flash Point | 132.459°C |
Solubility | soluble in Methanol |
Vapor Presure | 0.002mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Light yellow to Light orange |
BRN | 2969618 |
pKa | 13.49±0.70(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.583 |
Risk Codes | R22 - Harmful if swallowed R43 - May cause sensitization by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 9/PG 3 |
WGK Germany | 3 |
HS Code | 29242990 |
Hazard Class | IRRITANT |
preparation | in a ML three-necked flask equipped with a stirrer and a dropping funnel, add 16.2g of sodium hydroxide and 40ml of distilled water, dissolve with constant stirring and cool to 5 °c with cold water. Under constant stirring, 15.7g of bromine was added, and after addition, stirring was continued for 20min to completely react the bromine to obtain a NaOH-NaOBr mixed solution. The 4-aminobenzamide synthesized in the previous step was dissolved in 50ml of distilled water, and the 4-aminobenzamide solution was gradually added dropwise with constant stirring at a low temperature. After completion of the dropwise addition, the rearrangement reaction was performed, and the reaction temperature was controlled at 30 ° C., and the reaction was maintained for 30min. Then, the temperature was slowly raised, and the reaction temperature was controlled at about 85 ° C., and the reaction was continued for 35min. 10.4g of p-phenylenediamine was obtained by cooling and Suction filtration, and the filtrate was extracted with diethyl ether and dried under vacuum. The yield was 97.6% and the purity was 99.6%, after dropping and reacting for 15 hours, the solvent was distilled off under reduced pressure, and the concentrate was chromatographed on a silica gel column [eluent: V (ethyl acetate)/V (petroleum ether)]. = 1/10] compound specific carbamate enzyme was purified. |