4-(TriMethylsilyl)butan-1-ol - Names and Identifiers
4-(TriMethylsilyl)butan-1-ol - Physico-chemical Properties
Molecular Formula | C7H18OSi
|
Molar Mass | 146.3 |
Density | 0.830 g/cm3(Temp: 25 °C) |
Boling Point | 96 °C(Press: 25 Torr) |
Flash Point | 65.6°C |
Vapor Presure | 0.247mmHg at 25°C |
pKa | 15.27±0.10(Predicted) |
Refractive Index | 1.418 |
4-(TriMethylsilyl)butan-1-ol - Introduction
4-(Trimethylsilyl)butan-1-ol(4-(Trimethylsilyl)butan-1-ol) is an organosilicon compound with the following properties:
1. Appearance: colorless liquid
2. Molecular formula: C8H20OSi
3. Molecular weight: 160.33g/mol
4. Melting point:-90 ° C
5. Boiling point: 97-98 ° C
6. Density: 0.84 g/cm
7. Solubility: Soluble in organic solvents such as ethanol, ether and chloroform
4-(Trimethylsilyl)butan-1-ol has the following uses in organic synthesis:
1. As a protecting group: 4-(Trimethylsilyl)butan-1-ol can be used as a reagent for protecting alcohol or hydroxyl group, and plays the role of protecting other groups in organic synthesis.
2. Synthesis of organic silicon compounds: 4-(Trimethylsilyl)butan-1-ol can react to generate other organic silicon compounds, such as silicon ether and organic silicon heterocyclic compounds.
3. As a catalyst: 4-(Trimethylsilyl)butan-1-ol can be used as a chiral catalyst and play an important role in asymmetric synthesis.
The preparation method of 4-(Trimethylsilyl)butan-1-ol can be obtained by hydroxylation reaction. One synthetic method is the reaction of 3-bromobutanol with trimethylchlorosilane under alkaline conditions to produce 4-(Trimethylsilyl)butan-1-ol.
Regarding safety information, 4-(Trimethylsilyl)butan-1-ol may cause irritation to the eyes, skin and respiratory tract. Appropriate safety measures, such as wearing protective glasses, gloves and protective masks, are required during use. At the same time, it should be used in a well-ventilated place and avoid contact with fire sources. If accidental contact or ingestion occurs, the corresponding area should be cleaned immediately and medical help should be sought.
Last Update:2024-04-10 22:29:15