4-(Trifluoromethyl)quinolin-2-amine

4-(Trifluoromethyl)quinolin-2-amine - Names and Identifiers

Name	4-(Trifluoromethyl)quinolin-2-amine
Synonyms	4-(Trifluoromethyl)quinolin-2-amine 4-(trifluoromethyl)-2-quinolinamine 2-quinolinamine, 4-(trifluoromethyl)- 2-Quinolinamine, 4-(trifluoromethyl)-
CAS	211449-19-3
InChI	InChI=1/C10H7F3N2/c11-10(12,13)7-5-9(14)15-8-4-2-1-3-6(7)8/h1-5H,(H2,14,15)

4-(Trifluoromethyl)quinolin-2-amine - Physico-chemical Properties

Molecular Formula	C10H7F3N2
Molar Mass	212.17
Density	1.390
Boling Point	315 ºC
Flash Point	144 ºC
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C(protect from light)
Refractive Index	1.589

4-(Trifluoromethyl)quinolin-2-amine - Risk and Safety

Risk Codes	23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description	36/37 - Wear suitable protective clothing and gloves.
HS Code	29334900

4-(Trifluoromethyl)quinolin-2-amine - Introduction

4-(Trifluoromethyl)quinolin-2-amine is an organic compound with the chemical formula C10H6F3N. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White solid
-Melting point: About 120-130 degrees Celsius
-Boiling point: about 350 degrees Celsius
-Stability: Stable at room temperature, but decomposition may occur when encountering high temperature, light or oxygen.

Use:
4-(Trifluoromethyl)quinolin-2-amine has a wide range of applications, including:
-Important intermediates in chemical synthesis: can be used to synthesize other fluorine-containing organic compounds and drugs.
-Drug research and development: It has potential biological activity and can be used for research and development of new drugs.
-Pesticides and insecticides: raw materials that can be used to prepare pesticides and insecticides.

Method:
At present, there is no direct large-scale industrial preparation method report. However, the compound can be synthesized by the following steps:
1. 2-Aminoquinoline is reacted with trifluoromethane to give 4-(Trifluoromethyl)quinolin-2-amine.

Safety Information:
-The compound should be handled with precautions such as wearing suitable protective gloves, glasses and protective clothing.
-Avoid prolonged or repeated contact with substances to avoid allergies or irritation.
-Avoid contact with oxygen, strong oxidants and combustibles during storage and use to reduce the risk of fire or explosion.
-If contact or inhalation occurs, immediate medical attention should be given.

Last Update：2024-04-09 02:00:44