4-AMINO-2,3-DIFLUOROBENZOTRIFLUOROIDE
4-Amino-2,3-difluorobenzotrifluoride
CAS: 123950-46-9
Molecular Formula: C7H4F5N
4-AMINO-2,3-DIFLUOROBENZOTRIFLUOROIDE - Names and Identifiers
| Name | 4-Amino-2,3-difluorobenzotrifluoride |
| Synonyms | 5-Amino-2,4-difluorobenzotrifluoride 4-Amino-2,3-difluorobenzotrifluoride 4-AMINO-2,3-DIFLUOROBENZOTRIFLUOROIDE 2.3-DIFLUORO 4-TRIFLUOROMETHOXYANILINE 2,3-Difluoro-4-(trifluoromethyl)aniline 2,3-difluoro-4-(trifluoroMethyl)benzenaMine Benzenamine, 2,3-difluoro-4-(trifluoromethyl)- |
| CAS | 123950-46-9 |
| InChI | InChI=1/C7H4F5N/c8-5-3(7(10,11)12)1-2-4(13)6(5)9/h1-2H,13H2 |
4-AMINO-2,3-DIFLUOROBENZOTRIFLUOROIDE - Physico-chemical Properties
| Molecular Formula | C7H4F5N |
| Molar Mass | 197.11 |
| Density | 1.474±0.06 g/cm3(Predicted) |
| Boling Point | 188.0±40.0 °C(Predicted) |
| Flash Point | 76.9°C |
| Vapor Presure | 0.612mmHg at 25°C |
| pKa | 0.35±0.10(Predicted) |
| Refractive Index | 1.443 |
4-AMINO-2,3-DIFLUOROBENZOTRIFLUOROIDE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
4-AMINO-2,3-DIFLUOROBENZOTRIFLUOROIDE - Introduction
4-amino -2,3-difluorobenzotrifluoride, chemical formula is C7H6F5N. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
4-Amino -2, 3-difluorobenzotrifluoride is an organic compound having the form of a white to pale yellow crystalline solid. It has a melting point of about 140-143°C and a molecular weight of about 207.13g/mol. At room temperature, it is stable.
Use:
4-Amino -2, 3-difluorobenzotrifluoride is often used as a pharmaceutical intermediate, especially in the manufacture of antipsychotic drugs play an important role. It is also a good reducing agent and is widely used in organic synthesis. In addition, it can also be used in the manufacture of dyes, pigments and high-grade fluorosilicone rubber.
Preparation Method:
The preparation of 4-amino -2, 3-difluorobenzotrifluoride is generally accomplished by a multi-step reaction. A possible preparation method is to first react 2,3-difluorobenzotrifluoride with nitric acid to generate a para-nitro compound, and then perform a reduction reaction to obtain 4-amino -2,3-difluorobenzotrifluoride.
Safety Information:
4-amino -2, 3-difluorobenzotrifluoride is generally relatively safe under normal use conditions, but the following points should be paid attention to: avoid contact with strong oxidants and strong bases, and avoid prolonged or large amounts of inhalation Or contact with skin and eyes. Use appropriate protective equipment, such as chemical protective gloves and goggles. When using and handling, please refer to relevant safety data and operating specifications, and ensure that appropriate laboratory safety operations are followed.
Nature:
4-Amino -2, 3-difluorobenzotrifluoride is an organic compound having the form of a white to pale yellow crystalline solid. It has a melting point of about 140-143°C and a molecular weight of about 207.13g/mol. At room temperature, it is stable.
Use:
4-Amino -2, 3-difluorobenzotrifluoride is often used as a pharmaceutical intermediate, especially in the manufacture of antipsychotic drugs play an important role. It is also a good reducing agent and is widely used in organic synthesis. In addition, it can also be used in the manufacture of dyes, pigments and high-grade fluorosilicone rubber.
Preparation Method:
The preparation of 4-amino -2, 3-difluorobenzotrifluoride is generally accomplished by a multi-step reaction. A possible preparation method is to first react 2,3-difluorobenzotrifluoride with nitric acid to generate a para-nitro compound, and then perform a reduction reaction to obtain 4-amino -2,3-difluorobenzotrifluoride.
Safety Information:
4-amino -2, 3-difluorobenzotrifluoride is generally relatively safe under normal use conditions, but the following points should be paid attention to: avoid contact with strong oxidants and strong bases, and avoid prolonged or large amounts of inhalation Or contact with skin and eyes. Use appropriate protective equipment, such as chemical protective gloves and goggles. When using and handling, please refer to relevant safety data and operating specifications, and ensure that appropriate laboratory safety operations are followed.
Last Update：2024-04-09 20:52:54
