4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE

4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE - Names and Identifiers

Name	4-Amino-2-bromopyrimidine-5-carbonitrile
Synonyms	4-AMINO-2-BROMO-5-CYANOPYRIMIDINE 2-BROMO-4-AMINO-5-CYANOPYRIMIDINE 4-Amino-2-bromopyrimidine-5-carbonitrile 4-Amino-2-bromo-5-pyrimidinecarbonitrile 4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE 5-Pyrimidinecarbonitrile, 4-amino-2-bromo- 4-Amino-2-bromo-5-cyanopyrimidine, 4-Amino-2-bromo-5-cyano-1,3-diazine 4-Amino-2-bromo-pyrimidine-5-carbonitrile 4-Amino-2-bromo-pyrimidine-5-carbonitrile 4-Amino-2-bromo-pyrimidine-5-carbonitrile
CAS	94741-70-5
InChI	InChI=1/C5H3BrN4/c6-5-9-2-3(1-7)4(8)10-5/h2H,(H2,8,9,10)

4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE - Physico-chemical Properties

Molecular Formula	C5H3BrN4
Molar Mass	199.01
Density	1.944g/cm³
Melting Point	254°C (dec.)(lit.)
Boling Point	457.658°C at 760 mmHg
Flash Point	230.584°C
Vapor Presure	0mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.67

4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Note	Irritant

4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE - Introduction

It is an organic compound with the formula C5H3BrN4. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: It is a solid, usually in the form of white or off-white crystals.
-Melting point: The melting point of this compound is about 218-221°C.
-Solubility: The solubility in water is low, but it has good solubility in some organic solvents (such as methanol, ethanol, dimethyl ketone, etc.).

Use:
-Chemical reagents: often used as intermediates and reagents in organic synthesis.
-Drug research: The compound can be used in the development and research of new drugs in the field of medicine.

Preparation Method: The preparation of
can be carried out by the following reaction steps:
1.3-Amino -2-bromopyrimidine is reacted with dimethyl sulfoxide in an appropriate solvent and heated to an appropriate temperature under a protective atmosphere to generate 2-bromo-3-aminopyrimidine.
2. react 2-bromo-3-aminopyrimidine with sodium cyanide to obtain pyridine.

Safety Information:
-must belong to organic cyanide compounds, have certain toxicity, should avoid inhalation, swallowing or direct contact.
-Appropriate personal protective measures such as chemical protective gloves, goggles and respiratory protection should be taken when using the compound.
-should be stored in a dry, well-ventilated place, away from fire and flammable materials.

Last Update：2024-04-09 02:00:49