Name | 4-Aminotetrahydropyran |
Synonyms | 4-Aminotetrahyropyran 4-Aminotetrahydropyran 4-AMINOTETRAHYDROPYRAN TETRAHYDRO-PYRAN-4-YLAMINE 4-Aminotetrahydro-2H-pyran tetrahydro-2H-pyran-4-amine TETRAHYDRO-2H-PYRAN-4-AMINE tetrahydro-2H-pyran-4-aminium 2H-PYRAN-4-AMINE, TETRAHYDRO- TETRAHYDRO-2H-PYRAN-4-YLAMINE 2H-Pyran-4-amine,tetrahydro-(9CI) 2-amino-1-(4-chlorophenyl)ethanone 4-AMINOTETRAHYDROPYRAN 4-AMINOTETRAHYDRO-2H-PYRAN |
CAS | 38041-19-9 |
EINECS | 615-758-3 |
InChI | InChI=1/C5H11NO/c6-5-1-3-7-4-2-5/h5H,1-4,6H2/p+1 |
InChIKey | AHVQYHFYQWKUKB-UHFFFAOYSA-N |
Molecular Formula | C5H11NO |
Molar Mass | 101.15 |
Density | 0.977 g/cm3 at 25 °C |
Boling Point | 60 °C |
Flash Point | 54°C |
Vapor Presure | 3.68mmHg at 25°C |
pKa | 9.63±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | n20/D 1.463 |
Risk Codes | R10 - Flammable R34 - Causes burns R41 - Risk of serious damage to eyes R22 - Harmful if swallowed R37/18 - |
Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection. |
UN IDs | 2734 |
WGK Germany | 1 |
HS Code | 29321900 |
Hazard Class | IRRITANT |
Packing Group | Ⅲ |
application | 4-aminotetrahydropyran can be used as an intermediate in organic synthesis and a pharmaceutical intermediate, mainly used in laboratory research and development processes and chemical and pharmaceutical synthesis processes. |
Preparation | 4-methylamidotetrahydropyran is synthesized from 4-cyanotetrahydropyran and sodium hydroxide solution (or potassium hydroxide solution) as raw materials, Then slowly add sodium hypochlorite solution (or sodium hypobromite solution) to 4-formamotetrahydropyran, and then heat up until reflux, decarboxylation produces the product 4-aminotetrahydropyran. All reaction raw materials are put into a pot for reaction, and 4-aminotetrahydropyran is synthesized by selecting appropriate reaction conditions. |