4-Acetyl-2-chlorobenzonitrile - Names and Identifiers
4-Acetyl-2-chlorobenzonitrile - Physico-chemical Properties
4-Acetyl-2-chlorobenzonitrile - Upstream Downstream Industry
4-Acetyl-2-chlorobenzonitrile - Introduction
Benzonitril, 4-acetyl-2-chloro-is an organic compound with the chemical formula C10H8ClNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Melting point:-35 ° C
-Boiling point: 221-222 ° C
-Density: 1.20g/cm³
-Solubility: Soluble in alcohols, ethers, chlorinated hydrocarbons and esters, slightly soluble in water
Use:
-benzonitril, 4-acetyl-2-chloro-can be used as starting materials and intermediates in organic synthesis. It can be used to synthesize drugs, dyes, fragrances and other organic compounds.
-In organic synthesis, it can be used to prepare various nitrogen-containing organic compounds, such as piperazine and pyrazole compounds.
Method:
Generally, benzonitril, 4-acetyl-2-chloro-can be prepared by the following reaction:
1. First benzoic acid and anhydrous aluminum chloride reaction to generate benzoic acid chloride.
2. The benzoic acid chloride is then reacted with acetyl chloride to generate 4-acetyl benzoic acid chloride.
3. Finally, 4-acetyl benzoic acid chloride is reacted with silver chloride to obtain benzonitril, 4-acetyl-2-chloro-.
Safety Information:
-benzonitril, 4-acetyl-2-chloro-is an organic compound that requires careful handling.
-It is an irritating compound that may cause damage to the eyes, skin and respiratory system, so avoid direct exposure to the skin and eyes when in contact.
-During use, relevant safety procedures should be followed, including the wearing of appropriate personal protective equipment (e. G. Gloves, protective glasses, protective mask).
-During storage, it should be sealed and kept in a cool, dry place, away from fire and flammable materials.
Last Update：2024-04-09 21:00:56