4-Amino-2,6-dimethylpyridine - Names and Identifiers
Name | 2,6-dimethylpyridin-4-amine
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Synonyms | 4-Amino-2,6-lutidine 2,6-dimethylpyridin-4-amine 2,6-dimethyl-4-aminopyridin 4-Amino-2,6-dimethylpyridine 4-PyridinaMine, 2,6-diMethyl- (2,6-dimethyl-4-pyridyl)amine 2,6-DIMETHYL-PYRIDIN-4-YLAMINE 2,6-Dimethyl-Pyridin-4-Ylamine
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CAS | 3512-80-9
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EINECS | 222-515-1 |
InChI | InChI=1/C7H10N2/c1-5-3-7(8)4-6(2)9-5/h3-4H,1-2H3,(H2,8,9) |
4-Amino-2,6-dimethylpyridine - Physico-chemical Properties
Molecular Formula | C7H10N2
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Molar Mass | 122.17 |
Density | 1.0289 (estimate) |
Melting Point | 191.0 to 195.0 °C |
Boling Point | 246°C(lit.) |
Flash Point | 126.457°C |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.027mmHg at 25°C |
Appearance | Solid |
Color | White to Light yellow |
Maximum wavelength(λmax) | ['262nm(MeOH)(lit.)'] |
pKa | 10.30±0.50(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.5663 (estimate) |
MDL | MFCD00130078 |
4-Amino-2,6-dimethylpyridine - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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UN IDs | UN2811 |
HS Code | 29333990 |
Hazard Class | 6.1 |
4-Amino-2,6-dimethylpyridine - Introduction
2,6-dimethylpyridin-4-amine is an organic compound with the chemical formula C8H12N2. It is a pale yellow solid with a special amino and pyridine ring structure.
Its main uses include:
1. as a catalyst and ligand in organic synthesis, used in catalytic reaction, synthesis of drugs and dyes and other organic compounds;
2. As a preservative and antioxidant, used to extend the shelf life of cosmetics and food;
3. used as pharmaceutical intermediates for the synthesis of certain drugs.
The method of preparing 2,6-dimethylpyridin-4-amine is usually through the following steps:
1. First, mix 2,6-lutidine and nitric acid, and carry out nitration reaction at low temperature to obtain 2,6-dimethyl-4-nitropyridine;
2. Then 2,6-dimethyl-4-nitropyridine is reacted with sulfurous acid and ammonia for reduction reaction to obtain the final product 2,6-dimethylpyridin-4-amine.
Regarding its safety information, 2,6-dimethylpyridin-4-amine is an organic compound with certain potential hazards. Wear appropriate personal protective equipment such as gloves, protective glasses and laboratory coats when using or handling. Also avoid inhalation, ingestion or contact with skin. In case of accidental contact, rinse immediately with plenty of water and consult a doctor.
Please note that the above information is for reference only. Please follow the corresponding safety procedures and guidelines for specific use and operation.
Last Update:2024-04-09 21:54:55