4-Amino-5-(formamidomethyl)-2-methylpyrimidine - Names and Identifiers
4-Amino-5-(formamidomethyl)-2-methylpyrimidine - Physico-chemical Properties
Molecular Formula | C7H10N4O
|
Molar Mass | 166.18 |
Density | 1.245±0.06 g/cm3(Predicted) |
Melting Point | 227-228 °C |
Boling Point | 452.0±35.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Very Slightly, Sonicated) |
Appearance | Solid |
Color | Off-White to Pale Yellow |
pKa | 14.77±0.23(Predicted) |
Storage Condition | Amber Vial, -20°C Freezer, Under inert atmosphere |
Stability | Air Sensitive, Light Sensitive |
4-Amino-5-(formamidomethyl)-2-methylpyrimidine - Introduction
4-Amino-5-(formamidomethyl)-2-methylpyrimidine(4-Amino-5-(formamidomethyl)-2-methylpyrimidine) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C8H12N4O
-Molecular weight: 188.21g/mol
-Melting point: 173-175 degrees Celsius
-Solubility: Soluble in methanol, ethanol and water
Use:
4-Amino-5-(formamidomethyl)-2-methylpyrimidine has certain application value in medicinal chemistry and organic synthesis, and can be used to synthesize other organic compounds and drugs. It is often used as an intermediate in the synthesis of important bioactive substances, such as anticancer drugs and antiviral drugs.
Preparation Method:
4-Amino-5-(formamidomethyl)-2-methylpyrimidine is synthesized as follows:
1.2-methyl -4, 5-diaminopyrimidine reacts with formamide to give 4-amino -5-(formamidomethyl)-2-methyl pyrimidine.
2. The obtained product is subjected to deprotection reaction to obtain 4-Amino-5-(formamidomethyl)-2-methylrimidine.
Safety Information:
-Because the compounds have different physical and chemical properties, it is necessary to comply with the corresponding safety procedures when using them.
-Wear appropriate protective equipment when using chemicals, such as lab gloves, glasses, etc.
-Avoid direct contact with skin, eyes and mucous membranes, and maintain a well-ventilated environment.
-In the event of accidental inhalation or ingestion, seek immediate medical assistance and bring the packaging or label of the compound.
Last Update:2024-04-09 21:04:16