4-Benzyloxyindole

4-Benzyloxyindole - Names and Identifiers

Name	4-Benzyloxyindole
Synonyms	NSC 92539 4-Benzyloxyindole 4-BENZYLOXYINDOLE 4-BENZYLOXYLINDOLE 4-BENZYLOXY-1H-INDOLE 4-(benzyloxy)-1H-indole 4-(phenylmethoxy)-1h-indole 4-(Phenylmethoxy)-1H-indole {[(1H-Indol-4-yl)oxy]methyl}benzene
CAS	20289-26-3
EINECS	243-690-0
InChI	InChI=1/C15H13NO/c1-2-5-12(6-3-1)11-17-15-8-4-7-14-13(15)9-10-16-14/h1-10,16H,11H2

4-Benzyloxyindole - Physico-chemical Properties

Molecular Formula	C15H13NO
Molar Mass	223.27
Density	1.0707 (rough estimate)
Melting Point	57-61 °C (lit.)
Boling Point	364.56°C (rough estimate)
Flash Point	148.9°C
Solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Vapor Presure	1.31E-06mmHg at 25°C
Appearance	White to off-white powder
Color	Beige to Brown
BRN	183150
pKa	17.17±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5500 (estimate)
MDL	MFCD00047200
Physical and Chemical Properties	melting point 58-62°C

4-Benzyloxyindole - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29339990
Hazard Class	IRRITANT

4-Benzyloxyindole - Reference Information

Use

Used for the location-selective synthesis of oxopyrrolidine analogs through iodine-catalyzed Markovnikov addition reaction; used in medicinal chemistry, through the Bartoli of reductive cyclization reaction, the preparation of useful indole intermediates; used for the synthesis of carbon -11 labeled 4-aryl-4H chromene, as a new PET adjuvant for imaging dead cells in cancer; used to prepare HCV inhibitors; used to prepare 3-indolyl tetramethylcycloacetone as a CB2 cannabis receptor ligand; used to prepare 4-aryl-4H-chromene, as an inducer of apoptosis

Last Update：2024-04-09 20:52:54