4-Borono-1-bromo-2,3-difluorobenzene

4-Borono-1-bromo-2,3-difluorobenzene - Names and Identifiers

Name	4-Bromo-2,3-difluorobenzeneboronic acid
Synonyms	4-Borono-1-bromo-2,3-difluorobenzene 2,3-DIFLUORO-4-BROMOPHENYLBORONICACID 4-Bromo-2,3-difluorophenylboronic acid 4-BROMO-2,3-DIFLUOROPHENYLBORONIC ACID 4-BROMO-2,3-DIFLUOROBENZENEBORONIC ACID 4-Bromo-2,3-difluorobenzeneboronic acid B-(4-Bromo-2,3-difluorophenyl)boronic acid Boronic acid, (4-bromo-2,3-difluorophenyl)- (9CI)
CAS	374790-99-5
InChI	InChI=1/C6H4BBrF2O2/c8-4-2-1-3(7(11)12)5(9)6(4)10/h1-2,11-12H

4-Borono-1-bromo-2,3-difluorobenzene - Physico-chemical Properties

Molecular Formula	C6H4BBrF2O2
Molar Mass	236.81
Density	1.82
Melting Point	225°C
Boling Point	312.6°C at 760 mmHg
Flash Point	142.8°C
Vapor Presure	0.000224mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.547
MDL	MFCD02093065

4-Borono-1-bromo-2,3-difluorobenzene - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
Hazard Note	Irritant

4-Borono-1-bromo-2,3-difluorobenzene - Introduction

4-Bromo-2,3-difluorobenzeneboronic acid is an organic compound with the chemical formula C6H4BrBF2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-Bromo-2,3-difluorobenzeneboronic acid is a white or off-white solid.
-Solubility: It is insoluble in water, but soluble in organic solvents such as ethanol and dimethyl sulfoxide.
-Melting point: Its melting point is about 220-224°C.

Use:
- 4-Bromo-2,3-difluorobenzeneboronic acid is an organic boronic acid reagent, commonly used in organic synthesis and catalytic reactions.
-It is a commonly used ligand that can be used in organometallic catalyzed reactions, such as palladium-catalyzed cross-coupling reactions.

Preparation Method:
- 4-Bromo-2,3-difluorobenzeneboronic acid can be obtained by the reaction of lithium benzofuran and bromodifluorobenzene borate.

Safety Information:
- 4-Bromo-2,3-difluorobenzeneboronic acid specific hazards and safety instructions according to its use environment and conditions.
-Avoid inhalation, contact with skin or eyes, and maintain good ventilation.
-Before use, please check the relevant safety data sheet and operation guide, and take appropriate protective measures.
-Observe proper handling and management of chemicals during handling and storage.

Last Update：2024-04-10 22:29:15