4-Bromo-3-(trifluoromethyl)pyrazole

4-Bromo-3-(trifluoromethyl)pyrazole - Names and Identifiers

Name	4-bromo-3(trifluoromethyl)-1H-pyrazole
Synonyms	AKOS B018779 ART-CHEM-BB B018779 4-Bromo-3-(trifluoromethyl)pyrazole 4-Bromo-3-trifluoromethyl-1H-pyrazol 4-BROMO-3-TRIFLUOROMETHYL-1H-PYRAZOLE 4-bromo-3(trifluoromethyl)-1H-pyrazole 4-Bromo-5-(trifluoromethyl)-1H-pyrazole 4-Bromo-3-(trifluoromethyl)-1H-pyrazole 1H-Pyrazole,4-broMo-3-(trifluoroMethyl)- 1H-pyrazole, 4-bromo-5-(trifluoromethyl)- 1H-Pyrazole, 4-bromo-3-(trifluoromethyl)- 4-bromo-3(5)-(trifluoromethyl)-1H-pyrazole
CAS	19968-17-3
InChI	InChI=1/C4H2BrF3N2/c5-2-1-9-10-3(2)4(6,7)8/h1H,(H,9,10)

4-Bromo-3-(trifluoromethyl)pyrazole - Physico-chemical Properties

Molecular Formula	C4H2BrF3N2
Molar Mass	214.97
Density	1.942±0.06 g/cm3(Predicted)
Melting Point	105-107℃
Boling Point	235.3±35.0 °C(Predicted)
Flash Point	96.1°C
Vapor Presure	0.0774mmHg at 25°C
Appearance	Crystalline Powder
Color	White
pKa	9.27±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.48

4-Bromo-3-(trifluoromethyl)pyrazole - Risk and Safety

Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN2811
Hazard Class	IRRITANT

4-Bromo-3-(trifluoromethyl)pyrazole - Introduction

4-bromo-3(trifluoromethyl)-1H-pyrazole (BTFP) is an organic compound with the chemical formula C3BrF3N2. The following is a description of its nature, use, preparation and safety information:

Nature:
BTFP is a colorless to light yellow liquid with a pungent odor at room temperature. It has high thermal and chemical stability, and is not easily soluble in water, but soluble in organic solvents.

Use:
BTFP is mainly used in organic synthesis reaction substrates and reagents. It can be used as a strong fluorinating agent and brominating agent in some chemical reactions, and is often used in the substitution reaction of aromatic hydrocarbons and the synthesis of aromatic ethers.

Method:
The preparation method of BTFP is more complicated. A commonly used preparation method is obtained by two-step reaction of trifluoromethylation reaction and bromination reaction. First, under appropriate conditions, 3-trifluoromethylpyrazole is reacted with a brominating agent to give 4-bromo-3(trifluoromethyl)-1H-pyrazole.

Safety Information:
BTFP is an irritating compound that can cause skin and eye irritation. Avoid direct contact with skin and eyes during use, and operate in a well-ventilated place. In addition, BTFP is harmful to the environment and should be handled and disposed in accordance with the relevant regulations of environmental protection. As an organic compound, BTFP is flammable and should be kept away from open flames and high temperatures. During storage and handling, it is necessary to observe the relevant safety procedures.

Last Update：2024-04-10 22:29:15