4-Bromo-3-amino anisole - Names and Identifiers
4-Bromo-3-amino anisole - Physico-chemical Properties
Molecular Formula | C7H8BrNO
|
Molar Mass | 202.05 |
Density | 1.531±0.06 g/cm3(Predicted) |
Melting Point | 189-190°C |
Boling Point | 280.1±20.0 °C(Predicted) |
Flash Point | 123.173°C |
Vapor Presure | 0.004mmHg at 25°C |
Appearance | White powder |
pKa | 2.11±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.596 |
4-Bromo-3-amino anisole - Risk and Safety
Hazard Symbols | Xi - Irritant
|
HS Code | 29222990 |
4-Bromo-3-amino anisole - Introduction
2-Bromo-5-methoxyaniline is an organic compound with the chemical formula of C7H8BrNO and CAS number 58456-63-8. It is a colorless to pale yellow crystal. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: about 66-68 ℃
-Boiling point: about 250-300 ℃
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane, insoluble in water
Use:
- 2-Bromo-5-methoxyaniline can be used as catalysts and intermediates in organic synthesis reactions.
-It is also used to synthesize biologically active molecules in the pharmaceutical field.
Preparation Method:
The preparation method of 2-Bromo-5-methoxyaniline can be carried out by the following steps:
-First, dissolve p-methoxyaniline in an organic solvent.
-Then, add cuprous bromide (CuBr) and sodium bicarbonate anhydride (NaHCO3) to the solution.
-Under appropriate reaction conditions, react for several hours.
-After the reaction is completed, the product is purified by water washing and distillation.
Safety Information:
- 2-Bromo-5-methoxyaniline is an organic compound, and laboratory safety regulations should be followed during operation.
-It may cause irritation to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, safety glasses and masks during operation.
-During storage and handling, care should be taken to avoid contact with oxidants, strong acids or strong bases to avoid dangerous chemical reactions.
-When disposing of waste, follow local environmental regulations and choose the appropriate disposal method.
Last Update:2024-04-09 21:01:54