4-Bromo-5-methylisoxazole

4-Bromo-5-methylisoxazole - Names and Identifiers

Name	4-Bromo-5-methylisoxazole
Synonyms	4-Bromo-5-methylisoxazole 4-bromo-5-methyl-1,2-oxazole Isoxazole, 4-bromo-5-methyl- Isoxazole, 4-bromo-5-methyl- (6CI,7CI,8CI,9CI) ethyl 1-(5-cyano-3-{[3-(3-methoxypropyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]methyl}-4-methyl-6-oxo-1-propyl-1,6-dihydropyridin-2-yl)piperidine-3-carboxylate
CAS	7064-37-1
InChI	InChI=1/C4H4BrNO/c1-3-4(5)2-6-7-3/h2H,1H3

4-Bromo-5-methylisoxazole - Physico-chemical Properties

Molecular Formula	C4H4BrNO
Molar Mass	161.98
Density	1.569 g/cm3(Temp: 23 °C)
Boling Point	147-148℃
Flash Point	74.948°C
Vapor Presure	0.462mmHg at 25°C
pKa	-3.63±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.4915 (589.3 nm 20℃

4-Bromo-5-methylisoxazole - Introduction

4-Bromo-5-methylisoxazole(4-Bromo-5-methylisoxazole) is an organic compound with the chemical formula C4H4BrNO. It is a colorless to pale yellow crystal with a peculiar odor.

This compound is often used as an important intermediate in the field of medicine and chemical industry. In medicine, it can be used to synthesize some drugs and bioactive molecules, such as antibiotics, anticancer drugs, antibacterial drugs, etc. In the chemical industry, it can be used as a catalyst for organic synthesis reactions and participate in environmentally friendly catalysis of chemical reactions.

The preparation of 4-Bromo-5-methylisoxazole can be carried out by a variety of methods. A common synthetic method is to generate methylisoxazole in the reaction of N-bromopropionamide and ethylene oxide, and then react with hydrogen bromide under acidic conditions to obtain the target product.

Regarding safety information, 4-Bromo-5-methylisoxazole is irritating and corrosive at higher concentrations. Observe appropriate safety measures, such as wearing appropriate protective gloves, glasses and protective clothing, and avoid direct contact with skin, eyes and mucous membranes. The compound must be stored and disposed of properly to prevent it from posing a hazard to the environment. In case of any doubt or difficulties, it is recommended to consult a chemical specialist or refer to the safety data form for the chemical.

Last Update：2024-04-09 20:02:46