4-Bromo-6-methoxyquinoline - Names and Identifiers
4-Bromo-6-methoxyquinoline - Physico-chemical Properties
Molecular Formula | C10H8BrNO
|
Molar Mass | 238.08 |
Density | 1.516±0.06 g/cm3(Predicted) |
Melting Point | 106 °C |
Boling Point | 336.9±22.0 °C(Predicted) |
Flash Point | 157.5°C |
Vapor Presure | 0.000213mmHg at 25°C |
pKa | 3.42±0.16(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.64 |
4-Bromo-6-methoxyquinoline - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
|
WGK Germany | 3 |
4-Bromo-6-methoxyquinoline - Introduction
4-Bromo-6-methoxyquinoline(4-Bromo-6-methoxyquinoline) is an organic compound with the chemical formula C10H8BrNO. It is a yellow to orange-yellow crystalline substance.
Nature:
-Appearance: Yellow to orange-yellow crystal
-Melting point: 92-95°C
-Boiling point: 338.6°C
-Density: 1.46g/cm³
-Solubility: Slightly soluble in water, soluble in common organic solvents such as ethanol and dimethylformamide (DMF)
Use:
4-Bromo-6-methoxyquinoline has a wide range of applications in organic synthesis:
-As an intermediate: It can be used to synthesize other compounds, such as fluorescent dyes, pharmaceutical substances, pesticides, etc.
-Organic electroluminescent device (OLED): It can be used as one of the materials of OLED and participate in the preparation of organic light-emitting diodes (OLED).
Preparation Method:
The preparation method of 4-Bromo-6-methoxyquinoline is more complicated, and the commonly used method is synthesis by substitution reaction. One synthetic method is to react 6-methoxyquinoline with bromoacetic acid to produce the target product 4-Bromo-6-methoxyquinoline.
Safety Information:
4-Bromo-6-methoxyquinoline need to pay attention to the following safety matters when using:
-Contact with skin and eyes may cause irritation, direct contact should be avoided.
-Inhalation or ingestion may cause poisoning, should prevent inhalation of dust and ingestion.
-Operate in a well-ventilated area and wear appropriate protective equipment, such as lab gloves, goggles and masks.
-Observe chemical safety practices during storage and handling and keep them away from flammable materials.
Please note that the safe handling of chemicals should follow specific laboratory safety rules and regulations and follow the guidance of professionals.
Last Update:2024-04-09 19:05:49