4-Bromobenzylisothiocyanate

4-Bromobenzylisothiocyanate - Names and Identifiers

Name	Benzene,1-bromo-4-(isothiocyanatomethyl)-
Synonyms	Nsc137468 NSC137468 4-Bromobenzylisothiocyanate 4-Bromobenzyl isothiocyanate p-Bromobenzyl isothiocyanate Benzene,1-bromo-4-(isothiocyanatomethyl)- Isothiocyanicacid, p-bromobenzyl ester (6CI,7CI,8CI)
CAS	2076-56-4

4-Bromobenzylisothiocyanate - Physico-chemical Properties

Molecular Formula	C8H6BrNS
Molar Mass	228.11
Density	1.6550 (rough estimate)
Boling Point	308.5°Cat760mmHg
Flash Point	140.4°C
Water Solubility	14.83mg/L(25 ºC)
Refractive Index	1.6070 (estimate)

4-Bromobenzylisothiocyanate - Introduction

Benzene,1-bromo-4-(isothiocyyanatomethyl)-, chemical formula C9H7BrNS2O, is an organic compound. The following is a description of the nature, use, formulation and safety information of Benzene,1-bromo-4-(isothiocyyanatom):

Nature:
1. Appearance: colorless to light yellow solid.
2. Melting Point: about 40-42 degrees Celsius.
3. Boiling point: About 235 degrees Celsius.
4. Solubility: Slightly soluble in water, soluble in a variety of organic solvents.
5. Chemical properties: Benzene,1-bromo-4-(isothiocyanatomethyl)-is an organic sulfide, which can react with some electrophilic substances.

Use:
1. Benzene,1-bromo-4-(isothiocyanatomethyl)-is used as an intermediate in organic synthesis for the synthesis of other compounds.
2. In some pesticides and pharmaceutical fields, can also be used as raw materials.

Method:
The synthesis of Benzene,1-bromo-4-(isothiocyanatomethyl)-usually goes through the following steps:
1. Mix benzyl alcohol and tetramethyltrithiolaminomethane (protective agent) that are insoluble in water.
2. Add bromine to the mixture.
3. The reaction mixture is heated to react to form Benzene,1-bromo-4-(isothiocyanatomethyl)-.
4. Filter the product, wash and dry to obtain the pure product.

Safety Information:
1. Benzene,1-bromo-4-(isothiocyyanatom)-is irritating and corrosive, and should avoid contact with skin and eyes.
2. Wear appropriate protective equipment such as gloves, goggles and protective clothing during use and operation.
3. Avoid inhaling its dust or vapor.
4. Store in a dry and ventilated place, away from fire and flammable substances.
5. Be sure to handle and dispose of the compound properly in accordance with safe operation.

Last Update：2024-04-09 02:00:44