4-CARBOXY-3-NITROBENZYLAMINE
4-CARBOXY-3-NITROBENZYLAMINE
CAS: 100466-28-2
Molecular Formula: C8H8N2O4
4-CARBOXY-3-NITROBENZYLAMINE - Names and Identifiers
4-CARBOXY-3-NITROBENZYLAMINE - Physico-chemical Properties
| Molecular Formula | C8H8N2O4 |
| Molar Mass | 196.16 |
| Density | 1.466±0.06 g/cm3(Predicted) |
| Boling Point | 417.2±40.0 °C(Predicted) |
| pKa | 1.76±0.25(Predicted) |
4-CARBOXY-3-NITROBENZYLAMINE - Introduction
4-Aminomethyl-2-nitrobenzoic acid is an organic compound with the formula C8H8N2O4.
Nature:
4-aminomethyl-2-nitrobenzoic acid is a colorless or pale yellow crystal with an aromatic odor similar to benzoic acid. It is solid at room temperature, soluble in alcohol, ether and other organic solvents, slightly soluble in water.
Use:
4-Aminomethyl-2-nitrobenzoic acid is often used as an intermediate in the synthesis of organic dyes and fluorescent pigments. It can also be used as a fluorescent probe and a fluorescent labeled material in fluorescence microscopy. In addition, it can also be used to prepare pharmaceutical intermediates and biochemical reagents.
Preparation Method:
4-amino methyl -2-nitrobenzoic acid preparation method is more, one of the commonly used method is through the reduction of the nitrated toluene. The specific operation steps may be as follows: firstly, toluene and nitric acid are mixed, then concentrated sulfuric acid is used as a catalyst to carry out nitration reaction at low temperature; then, the reaction mixture is subjected to reduction reaction, and sodium nitrite or nitrite solution is used to reduce, and finally the target product 4-aminomethyl-2-nitrobenzoic acid is obtained.
Safety Information:
4-aminomethyl-2-nitrobenzoic acid may produce toxic gases when heated or in contact with strong oxidants. Inhalation should be avoided and contact with skin and eyes should be avoided. Appropriate personal protective equipment such as gloves, glasses and laboratory coats should be worn during operation. Pay attention to fire and explosion prevention measures during use, storage and handling, and ensure a well-ventilated environment. In the event of an accident or accidental contact, rinse immediately with plenty of water and seek medical help.
Nature:
4-aminomethyl-2-nitrobenzoic acid is a colorless or pale yellow crystal with an aromatic odor similar to benzoic acid. It is solid at room temperature, soluble in alcohol, ether and other organic solvents, slightly soluble in water.
Use:
4-Aminomethyl-2-nitrobenzoic acid is often used as an intermediate in the synthesis of organic dyes and fluorescent pigments. It can also be used as a fluorescent probe and a fluorescent labeled material in fluorescence microscopy. In addition, it can also be used to prepare pharmaceutical intermediates and biochemical reagents.
Preparation Method:
4-amino methyl -2-nitrobenzoic acid preparation method is more, one of the commonly used method is through the reduction of the nitrated toluene. The specific operation steps may be as follows: firstly, toluene and nitric acid are mixed, then concentrated sulfuric acid is used as a catalyst to carry out nitration reaction at low temperature; then, the reaction mixture is subjected to reduction reaction, and sodium nitrite or nitrite solution is used to reduce, and finally the target product 4-aminomethyl-2-nitrobenzoic acid is obtained.
Safety Information:
4-aminomethyl-2-nitrobenzoic acid may produce toxic gases when heated or in contact with strong oxidants. Inhalation should be avoided and contact with skin and eyes should be avoided. Appropriate personal protective equipment such as gloves, glasses and laboratory coats should be worn during operation. Pay attention to fire and explosion prevention measures during use, storage and handling, and ensure a well-ventilated environment. In the event of an accident or accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:50
