4-CHLORO-2-(TRIFLUOROMETHYL)PYRIDINE
2-trifluoromethyl-4-chloropyridine
CAS: 131748-14-6
Molecular Formula: C6H3ClF3N
4-CHLORO-2-(TRIFLUOROMETHYL)PYRIDINE - Names and Identifiers
| Name | 2-trifluoromethyl-4-chloropyridine |
| Synonyms | 4-Chloro-2-(TrifluoroMeth 2-TRIFLUOROMETHYL-4-CHLOROPYRIDINE 2-trifluoromethyl-4-chloropyridine 4-CHLORO-2-(TRIFLUOROMETHYL)PYRIDINE 4-chloro-2-(trifluoromethyl)pyridine Pyridine,4-chloro-2-(trifluoromethyl)- 2-Trifluoromethyl-4-Chloropyridine(WX636118) 4-Chloro-alpha,alpha,alpha-trifluoro-2-picoline |
| CAS | 131748-14-6 |
| EINECS | 1312995-182-4 |
| InChI | InChI=1/C6H3ClF3N/c7-4-1-2-11-5(3-4)6(8,9)10/h1-3H |
4-CHLORO-2-(TRIFLUOROMETHYL)PYRIDINE - Physico-chemical Properties
| Molecular Formula | C6H3ClF3N |
| Molar Mass | 181.54 |
| Density | 1.417 |
| Boling Point | 137.4±35.0 °C(Predicted) |
| Flash Point | 36.9°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 8.756mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless |
| pKa | -1.29±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.447 |
4-CHLORO-2-(TRIFLUOROMETHYL)PYRIDINE - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN2811 |
| Hazard Class | IRRITANT |
4-CHLORO-2-(TRIFLUOROMETHYL)PYRIDINE - Introduction
2-Trifluoromethyl-4-chloropyridine is an organic compound with the chemical formula C6H2ClF3N. The following is an introduction to its nature, use, preparation and safety information:
Nature:
2-Trifluoromethyl-4-chloropyridine is a colorless to pale yellow liquid with a pungent odor. It is stable at room temperature, but may decompose at high temperatures. It is practically insoluble in water and soluble in organic solvents such as ethanol, acetone and methanol.
Use:
2-Trifluoromethyl-4-chloropyridine is an important chemical intermediate, which is widely used in the fields of medicine, pesticide, dye and paint. It can be used as a raw material for the synthesis of other organic compounds and participate in various organic synthesis reactions, such as imidization and substitution reactions.
Preparation Method:
2-Trifluoromethyl-4-chloropyridine is usually prepared by chemical synthesis methods. One of the common methods is the reaction of 4-chloropyridine with trifluoroformate to produce 2-trifluoromethyl-4-chloropyridine.
Safety Information:
2-Trifluoromethyl-4-chloropyridine is an irritating chemical that may cause irritation in contact with the eyes, skin, and respiratory tract. Personal protective measures should be taken during use and handling, including wearing protective glasses, gloves and protective masks. If it comes into contact with skin or eyes, rinse immediately with plenty of water. In addition, 2-trifluoromethyl-4-chloropyridine should be stored in a sealed, dry, cool place, away from ignition and flammable materials.
Nature:
2-Trifluoromethyl-4-chloropyridine is a colorless to pale yellow liquid with a pungent odor. It is stable at room temperature, but may decompose at high temperatures. It is practically insoluble in water and soluble in organic solvents such as ethanol, acetone and methanol.
Use:
2-Trifluoromethyl-4-chloropyridine is an important chemical intermediate, which is widely used in the fields of medicine, pesticide, dye and paint. It can be used as a raw material for the synthesis of other organic compounds and participate in various organic synthesis reactions, such as imidization and substitution reactions.
Preparation Method:
2-Trifluoromethyl-4-chloropyridine is usually prepared by chemical synthesis methods. One of the common methods is the reaction of 4-chloropyridine with trifluoroformate to produce 2-trifluoromethyl-4-chloropyridine.
Safety Information:
2-Trifluoromethyl-4-chloropyridine is an irritating chemical that may cause irritation in contact with the eyes, skin, and respiratory tract. Personal protective measures should be taken during use and handling, including wearing protective glasses, gloves and protective masks. If it comes into contact with skin or eyes, rinse immediately with plenty of water. In addition, 2-trifluoromethyl-4-chloropyridine should be stored in a sealed, dry, cool place, away from ignition and flammable materials.
Last Update：2024-04-09 20:52:54
