4-CHLORO-2-FLUORO-6-IODOANILINE

4-CHLORO-2-FLUORO-6-IODOANILINE - Names and Identifiers

Name	4-Chloro-2-fluoro-6-iodoaniline
Synonyms	4-Chloro-6-fluoro-2-iodoaniline 4-CHLORO-2-FLUORO-6-IODOANILINE 4-Chloro-2-fluoro-6-iodoaniline Benzenamine,4-chloro-2-fluoro-6-iodo- 4- chloro- 2- fluoro- 6- iodo-Benzenamine
CAS	216393-67-8
EINECS	678-656-8
InChI	InChI=1/C6H4ClFIN/c7-3-1-4(8)6(10)5(9)2-3/h1-2H,10H2

4-CHLORO-2-FLUORO-6-IODOANILINE - Physico-chemical Properties

Molecular Formula	C6H4ClFIN
Molar Mass	271.46
Density	2.089±0.06 g/cm3(Predicted)
Melting Point	39-41°C
Boling Point	267.4±40.0 °C(Predicted)
Flash Point	115.5°C
Vapor Presure	0.00818mmHg at 25°C
pKa	0.51±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Sensitive	Light Sensitive
Refractive Index	1.665
MDL	MFCD01318122

4-CHLORO-2-FLUORO-6-IODOANILINE - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/38 - Irritating to eyes and skin. R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2811
Hazard Note	Harmful/Irritant
Hazard Class	6.1
Packing Group	III

4-CHLORO-2-FLUORO-6-IODOANILINE - Introduction

It is an organic compound with the chemical formula C6H4ClFIN. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: It is a white to light yellow crystalline solid.
-Solubility: Soluble in organic solvents, such as ethanol, dimethyl ether and chloroform, slightly soluble in water.
-Melting point: Its melting point range is 30-34 ° C.
-Density: about 2.06g/cm3.
-Toxicity: It is an organic halogen compound, which has certain toxicity and should be handled and used with care.

Use:
One of the main uses of calcium is as an intermediate in organic synthesis. It can be used to synthesize chemicals such as polymers, dyes, pesticides and pharmaceuticals. Because of its structure contains chlorine, fluorine and iodine atoms, it has an important influence on some specific reactions.

Method:
A common method of preparation is achieved by reducing, fluorinating and iodinating p-nitrochlorobenzene. The specific synthesis steps can include the following steps:

1. The reaction of p-nitrochlorobenzene with ammonium nitrite is reduced to p-amino chlorobenzene.
2. P-Aminochlorobenzene is fluorinated using hydrogen fluoride or hydrogen sulphite in the presence of a fluorinating agent.
3. In the presence of an iodinating agent, use sodium iodide or hydrogen iodide to iodinate fluorine, and finally synthesize the product.

Safety Information:
-is a chemical, with certain toxicity. Care should be taken to wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing during use or handling.
-Avoid contact with skin, eyes and mucous membranes. In case of accidental contact, rinse the affected area immediately with plenty of water and seek medical attention.
-It should be stored in a sealed container, away from fire and high temperature, and placed out of the reach of children.

Last Update：2024-04-09 21:04:16