4-CHLORO-3-BROMOPYRIDINE
3-Bromo-4-chloropyridine
CAS: 36953-42-1
Molecular Formula: C5H3BrClN
4-CHLORO-3-BROMOPYRIDINE - Names and Identifiers
| Name | 3-Bromo-4-chloropyridine |
| Synonyms | 4-CHLORO-3-BROMOPYRIDINE 3-BROMO-4-CHLOROPYRIDINE 3-Bromo-4-chloropyridine 3-BroMo-4-chloridepyridine Pyridine, 3-bromo-4-chloro- 3-broMo -4-chlorine pyridine |
| CAS | 36953-42-1 |
| EINECS | 690-646-5 |
| InChI | InChI=1/C5H3BrClN/c6-4-3-8-2-1-5(4)7/h1-3H |
4-CHLORO-3-BROMOPYRIDINE - Physico-chemical Properties
| Molecular Formula | C5H3BrClN |
| Molar Mass | 192.44 |
| Density | 1.19 |
| Melting Point | 17.5-18.5 °C |
| Boling Point | 115 °C(Press: 20 Torr) |
| Flash Point | 79.2°C |
| Vapor Presure | 0.326mmHg at 25°C |
| Appearance | Liquid After Melting |
| Color | Clear colorless to yellow |
| pKa | 1.74±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.453 |
| Physical and Chemical Properties | Light yellow liquid |
4-CHLORO-3-BROMOPYRIDINE - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/22 - Harmful by inhalation and if swallowed. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R25 - Toxic if swallowed |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection. |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
4-CHLORO-3-BROMOPYRIDINE - Introduction
3-Bromo-4-choropyridine is an organic compound with the chemical formula C5H3BrClN. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 3-Bromo-4-chloropyridine is a colorless to pale yellow crystal or pure white solid.
-Melting point: Its melting point is about 89-93 degrees Celsius.
-Boiling point: Its boiling point is about 220-230 degrees Celsius.
-Density: Its density is about 1.76-1.79g/cm3.
-Solubility: 3-Bromo-4-chloropyridine can be dissolved in organic solvents, such as ethanol and chloroform.
Use:
- 3-Bromo-4-chloropyridine is an important organic synthesis intermediate, commonly used in the synthesis of other organic compounds, such as pesticides, pharmaceuticals and dyes.
-It can also be used as a catalyst and coordination reagent.
Preparation Method:
- 3-Bromo-4-chloropyridine can be prepared by the reaction between pyridine and bromine and chlorine compounds. A common method is to react pyridine with hydrogen bromide under acidic conditions to give 3-bromopyridine, which is then chlorinated with ferrous chloride to give 3-Bromo-4-chloropyridine.
Safety Information:
- 3-Bromo-4-chloropyridine should be handled and stored to avoid inhalation, contact with skin and eyes, because it may cause irritation and damage to the human body.
-Wear personal protective equipment such as protective gloves, goggles and protective clothing during use.
-Operate in a well-ventilated place to avoid inhaling its vapor.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-Please use in strict accordance with the regulations and safety guidelines for chemicals.
Nature:
-Appearance: 3-Bromo-4-chloropyridine is a colorless to pale yellow crystal or pure white solid.
-Melting point: Its melting point is about 89-93 degrees Celsius.
-Boiling point: Its boiling point is about 220-230 degrees Celsius.
-Density: Its density is about 1.76-1.79g/cm3.
-Solubility: 3-Bromo-4-chloropyridine can be dissolved in organic solvents, such as ethanol and chloroform.
Use:
- 3-Bromo-4-chloropyridine is an important organic synthesis intermediate, commonly used in the synthesis of other organic compounds, such as pesticides, pharmaceuticals and dyes.
-It can also be used as a catalyst and coordination reagent.
Preparation Method:
- 3-Bromo-4-chloropyridine can be prepared by the reaction between pyridine and bromine and chlorine compounds. A common method is to react pyridine with hydrogen bromide under acidic conditions to give 3-bromopyridine, which is then chlorinated with ferrous chloride to give 3-Bromo-4-chloropyridine.
Safety Information:
- 3-Bromo-4-chloropyridine should be handled and stored to avoid inhalation, contact with skin and eyes, because it may cause irritation and damage to the human body.
-Wear personal protective equipment such as protective gloves, goggles and protective clothing during use.
-Operate in a well-ventilated place to avoid inhaling its vapor.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-Please use in strict accordance with the regulations and safety guidelines for chemicals.
Last Update：2024-04-09 15:17:57
