4-Carboxy-1H-indazole

4-Carboxy-1H-indazole - Names and Identifiers

Name	1H-Indazole-4-carboxylic acid
Synonyms	4-Carboxy-1H-indazole 4-INDAZOLECARBOXYLIC ACID 4-Indazolecarboxylic acid INDAZOLE-4-CARBOXYLIC ACID Indazole-4-carboxylic aci... 1H-Indazole-4-carboxylic acid 1H-INDAZOLE-4-CARBOXYLIC ACID 4-(1H)INDAZOLE CARBOXYLIC ACID 4-(1H)Indazole carboxylic acid 1H-Indazole-4-Carboxylic Acid(WX614188)
CAS	677306-38-6
InChI	InChI=1/C8H6N2O2/c11-8(12)5-2-1-3-7-6(5)4-9-10-7/h1-4H,(H,9,10)(H,11,12)

4-Carboxy-1H-indazole - Physico-chemical Properties

Molecular Formula	C8H6N2O2
Molar Mass	162.15
Density	1.506±0.06 g/cm3(Predicted)
Melting Point	ca 280℃
Boling Point	443.7±18.0 °C(Predicted)
Flash Point	222.172°C
Vapor Presure	0mmHg at 25°C
Appearance	Crystalline Powder
Color	White to cream
pKa	3.35±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.743
MDL	MFCD03840644

4-Carboxy-1H-indazole - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29339980

4-Carboxy-1H-indazole - Introduction

1H-Indazole-4-carboxylic acid is an organic compound with the chemical formula C8H6N2O2. It has the form of white crystals or crystalline powder.

This compound is widely used in chemical laboratories, mainly for organic synthesis and pharmaceutical research. It is an important raw material for the synthesis of indazole drugs, pesticides and dyes and other compounds. In addition, 1H-Indazole-4-carboxylic acid can also be used as a ligand for metal complexes.

There are various methods for preparing 1H-Indazole-4-carbonic acid. One commonly used method is to react 1H-indazole with carbon dioxide and sodium hydroxide. The specific steps include dissolving 1H-indazole in water, adding sodium hydroxide, and bubbling carbon dioxide gas into the reaction mixture, and finally 1H-Indazole-4-carboxylic acid can be obtained.

In terms of safety, 1H-Indazole-4-carboxylic acid should be used with the same care as any chemical. It may be irritating to the eyes and skin, so wear appropriate protective gloves and glasses during operation. In addition, inhalation or ingestion of the compound should be avoided and use in a well-ventilated area should be ensured. If ingestion or contact causes discomfort, seek medical attention immediately. Before using this compound, it is necessary to carefully read and comply with the safety data sheet (SDS) of the relevant chemical.

Last Update：2024-04-09 20:52:54