4-Carboxy-2,6-difluoroanisole
3,5-Difluoro-4-methoxybenzoic acid
CAS: 319-60-8
Molecular Formula: C8H6F2O3
4-Carboxy-2,6-difluoroanisole - Names and Identifiers
| Name | 3,5-Difluoro-4-methoxybenzoic acid |
| Synonyms | 319-60-8 QVR CF EF DO1 3,5-Difluoro-p-anisic acid 4-Carboxy-2,6-difluoroanisole 3,5-DIFLUORO-4-METHOXYBENZOIC ACID 3,5-Difluoro-4-methoxybenzoic acid Benzoic acid, 3,5-difluoro-4-methoxy- 3,5-difluoro-4-methoxybenbenzoic acid 4-Carboxy-2,6-difluoroanisole, 3,5-Difluoro-p-anisic acid |
| CAS | 319-60-8 |
| InChI | InChI=1/C8H6F2O3/c1-13-7-5(9)2-4(8(11)12)3-6(7)10/h2-3H,1H3,(H,11,12) |
4-Carboxy-2,6-difluoroanisole - Physico-chemical Properties
| Molecular Formula | C8H6F2O3 |
| Molar Mass | 188.13 |
| Density | 1.399 |
| Melting Point | 164-166°C |
| Boling Point | 286℃ |
| Flash Point | 127℃ |
| Vapor Presure | 0.00123mmHg at 25°C |
| pKa | 3.79±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.504 |
| MDL | MFCD01090994 |
4-Carboxy-2,6-difluoroanisole - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37 - Wear suitable gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29189900 |
| Hazard Note | Irritant |
4-Carboxy-2,6-difluoroanisole - Introduction
3. acid is an organic compound with the chemical formula C8H6F2O3. The following is a description of some properties, uses, preparation and safety information about this compound:
Nature:
-Appearance: White crystalline solid
-Melting point: 90-95 ° C
-Boiling point: 284 ° C
-Solubility: Soluble in organic solvents such as alcohols, ethers and esters
-specific gravity: 1.543g/cm³
Use:
3, acid has a wide range of applications in the field of medicine and pesticides.
-Medicine: can be used as an intermediate for the synthesis of certain drugs, such as non-steroidal anti-inflammatory drugs.
-Pesticides: can be used as raw materials and intermediates of pesticides.
Method:
3. acid can be prepared by the following methods:
1. 3,5-difluorobenzoic acid reacts with methoxylation reagent (such as methyl bromide, methyl iodide), and then undergoes ester hydrolysis to obtain the target product.
2. 3, 5-difluoromethylbenzene reacts with a methoxylation reagent, and then undergoes acid hydrolysis to obtain the target product.
Safety Information:
3. acid should pay attention to the following safety matters during storage and handling:
-Avoid contact with skin, eyes and respiratory tract to prevent irritation or injury.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during operation.
-Store in a dry, ventilated place away from sources of fire.
-Please dispose of the remaining material according to the correct waste disposal method.
Nature:
-Appearance: White crystalline solid
-Melting point: 90-95 ° C
-Boiling point: 284 ° C
-Solubility: Soluble in organic solvents such as alcohols, ethers and esters
-specific gravity: 1.543g/cm³
Use:
3, acid has a wide range of applications in the field of medicine and pesticides.
-Medicine: can be used as an intermediate for the synthesis of certain drugs, such as non-steroidal anti-inflammatory drugs.
-Pesticides: can be used as raw materials and intermediates of pesticides.
Method:
3. acid can be prepared by the following methods:
1. 3,5-difluorobenzoic acid reacts with methoxylation reagent (such as methyl bromide, methyl iodide), and then undergoes ester hydrolysis to obtain the target product.
2. 3, 5-difluoromethylbenzene reacts with a methoxylation reagent, and then undergoes acid hydrolysis to obtain the target product.
Safety Information:
3. acid should pay attention to the following safety matters during storage and handling:
-Avoid contact with skin, eyes and respiratory tract to prevent irritation or injury.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during operation.
-Store in a dry, ventilated place away from sources of fire.
-Please dispose of the remaining material according to the correct waste disposal method.
Last Update：2024-04-09 19:05:49
Supplier List
Spot supply
Product Name: Dotinurad Impurity 29 Visit Supplier Webpage Request for quotationCAS: 319-60-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 3,5-Difluoro-4-Methoxybenzoic Acid Visit Supplier Webpage Request for quotation
CAS: 319-60-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 319-60-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Dotinurad Impurity 29 Visit Supplier Webpage Request for quotationCAS: 319-60-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 3,5-Difluoro-4-Methoxybenzoic Acid Visit Supplier Webpage Request for quotation
CAS: 319-60-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 319-60-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History