4-Chloro-2,3-difluoro-pyridine

4-Chloro-2,3-difluoro-pyridine - Names and Identifiers

Name	4-chloro-2,3-difluoropyridine
Synonyms	4-chloro-2,3-difluoropyridine 2,3-dichloro-4-fluoropyridine 2,3-difluoro-4-chloro-pyridine 4-Chloro-2,3-difluoro-pyridine Pyridine,4-chloro-2,3-difluoro- pyridine, 4-chloro-2,3-difluoro-
CAS	851178-99-9
EINECS	200-158-5
InChI	InChI=1/C5H2ClF2N/c6-3-1-2-9-5(8)4(3)7/h1-2H

4-Chloro-2,3-difluoro-pyridine - Physico-chemical Properties

Molecular Formula	C5H2ClF2N
Molar Mass	149.53
Density	1.451±0.06 g/cm3(Predicted)
Melting Point	-25--23℃
Boling Point	141-142℃
Flash Point	44.497°C
Vapor Presure	5.001mmHg at 25°C
pKa	-0.47±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.4726 (589.3 nm 20℃

4-Chloro-2,3-difluoro-pyridine - Introduction

4-choro-2, 3-difluoropyridine is an organic compound with the chemical formula C5HClF2N. The following is a brief description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-choro-2, 3-difluoropyridine is a colorless to pale yellow liquid.
-Boiling point: Its boiling point is about 125°C.
-Solubility: It can be partially dissolved in water and soluble in most organic solvents.
-Stability: 4-choro-2, 3-difluoropyridine is stable at room temperature, but may explode in the presence of flame.

Use:
-Chemical intermediates: 4-Chloro-2, 3-difluoropyridine is commonly used as an intermediate in organic synthesis for the synthesis of various organic compounds.
-Pesticide: It can also be used to prepare pesticides, with properties such as insecticides and fungicides.

Preparation Method:
4-choro-2, 3-difluoropyridine is usually synthesized by the following steps:
1. First, a fluorine atom is introduced by a substitution reaction using pyridine as a starting material.
2. Then, on the basis of fluorinated pyridine, chlorine atoms are introduced through substitution or electrophilic addition reaction.

Safety Information:
-Effects on the human body: 4-chloro-2,3-difluoropyridine can enter the body through inhalation, skin contact or ingestion. It may cause irritation or corrosion to the skin, eyes and respiratory system. Prolonged or repeated exposure may be harmful to health and may have adverse effects on the reproductive system or the fetus.
-Safe handling: When using and handling 4-chloro-2,3-difluoropyridine, you should wear appropriate personal protective equipment, such as gloves, safety glasses and respiratory protection equipment. Contact with skin and eyes should be avoided, and inhalation of its vapors should be avoided.
-Storage and disposal: It should be stored in an airtight container, away from fire sources. Waste should be disposed of in accordance with local regulations.

Last Update：2024-04-10 22:29:15