4-Chloro-2,8-dimethylquinoline

4-Chloro-2,8-dimethylquinoline - Names and Identifiers

Name	4-Chloro-2,8-dimethylquinoline
Synonyms	4-CHLORO-8-METHYLQUINALDINE 4-Chloro-2,8-dimethylquinoline 4-CHLORO-2,8-DIMETHYLQUINOLINE 4-chloro-2,6-dimethylquinoline hydrochloride
CAS	32314-39-9
InChI	InChI=1/C11H10ClN/c1-7-4-3-5-9-10(12)6-8(2)13-11(7)9/h3-6H,1-2H3

4-Chloro-2,8-dimethylquinoline - Physico-chemical Properties

Molecular Formula	C11H10ClN
Molar Mass	191.66
Density	1.188
Melting Point	182-186 C
Boling Point	283.5°C at 760 mmHg
Flash Point	152.4°C
Vapor Presure	0.00538mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.621

4-Chloro-2,8-dimethylquinoline - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection.
WGK Germany	3

4-Chloro-2,8-dimethylquinoline - Introduction

4-choro-2, 8-dimethylquinoline is an organic compound with the chemical formula C12H11ClN. The following is an introduction to its nature, use, preparation and safety information:

Nature:
4-choro-2, 8-dimethylquinoline is a solid with the appearance of yellow crystals. It has a melting point of 68-70°C and a boiling point of 280-281°C. The compound is insoluble in water at room temperature, but soluble in most organic solvents, such as alcohols, ethers and ketones.

Use:
4-Chloro-2,8-dimethylquinoline is mainly used in the field of organic synthesis. It can be used as a pharmaceutical intermediate for the synthesis of antimalarial drugs and other compounds in the field of medicine. In addition, it can also be used as a precursor for dyes and optical brighteners.

Method:
The preparation of 4-Chloro-2,8-dimethylquinoline can be carried out by the following steps: First, 2,8-dimethylquinoline is reacted with sodium hypochlorite in the presence of cerium chloride to obtain 4-Chloro-2,8-dimethylquinoline.

Safety Information:
No detailed data have been reported on the toxicity and danger of 4-choro-2, 8-dimethylquinoline. However, as an organic compound, it may be irritating and dangerous to the human body. Therefore, during use and handling, appropriate safety precautions should be taken, such as wearing protective gloves, glasses and protective clothing, ensuring that the room is well ventilated, and avoiding inhalation, swallowing or skin contact. When used in laboratory and industrial environments, the relevant safety procedures and requirements for the safe storage of the compound should be observed.

Last Update：2024-04-09 21:01:54