4-Chloro-2-methyl-7H-pyrrolo

4-Chloro-2-methyl-7H-pyrrolo - Names and Identifiers

Name	4-Chloro-2-methyl-1H-pyrrolo[2,3-d]pyrimidine
Synonyms	-7H-pyrroL 4-Chloro-2-methyl-7H-pyr 4-Chloro-2-methyl-7H-pyrrolo 2-methyl-4-chloro-pyrrolopyrimidine 4-Chloro-2-methyl-1H-pyrrolo[2,3-d]pyrimidine 4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 7H-pyrrolo[2,3-d]pyrimidine, 4-chloro-2-methyl- 1H-pyrrolo[2,3-d]pyrimidine, 4-chloro-2-methyl- 1H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-2-methyl-
CAS	71149-52-5
InChI	InChI=1/C7H6ClN3/c1-4-10-6(8)5-2-3-9-7(5)11-4/h2-3H,1H3,(H,9,10,11)

4-Chloro-2-methyl-7H-pyrrolo - Physico-chemical Properties

Molecular Formula	C7H6ClN3
Molar Mass	167.6
Density	1.51±0.1 g/cm3(Predicted)
Melting Point	207-208 °C
Boling Point	290.5±50.0 °C(Predicted)
Flash Point	114.932°C
Vapor Presure	0.102mmHg at 25°C
Appearance	White solid
pKa	11.49±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.688
MDL	MFCD09746275

4-Chloro-2-methyl-7H-pyrrolo - Risk and Safety

Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	2811
WGK Germany	3
Hazard Class	6.1
Packing Group	Ⅲ

4-Chloro-2-methyl-7H-pyrrolo - Introduction

[2,3-d]pyrimidine is an organic compound with the chemical formula C7H5ClN4. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless crystalline solid
-melting point: 212-213 ℃
-Boiling point: 430.6 ℃
-Molecular weight: 192.59g/mol
-Solubility: Slightly soluble in ethanol and dimethyl sulfoxide, almost insoluble in water

Use:
[2,3-d]pyrimidine have important application value in the field of medicinal chemistry and can be used as intermediates of drug molecules.
-It has pyrimidine and pyrrole ring structures, which makes it potential in anti-tumor drug research. Studies have shown that the related compounds may exhibit anti-tumor activity and thus can be used as candidate compounds for anti-tumor drugs.
-In addition, it can also be used to synthesize other organic compounds and play an important role in materials science research.

Preparation Method:
[2,3-d]pyrimidine are generally prepared by chemical synthesis. A common synthesis method is to introduce methyl and chlorine groups on the pyrimidine ring.
-The specific synthesis method is more complicated. 3-acetylpyrimidine can be obtained by the reaction of pyrimidine and acetic anhydride, and then the target compound can be prepared by the treatment of lead nitrate and the related reaction.

Safety Information:
There are not many reports on the safety information of [2,3-d]pyrimidine, but as an organic compound, there may be some potential safety hazards:
-Avoid inhalation and skin contact, and take appropriate protective measures, including gloves, protective glasses and chemical-resistant work clothes.
-When using and handling this compound, care should be taken to follow the standard safe operating procedures for using and handling organic compounds.
-In the process of safe operation, it should be avoided to use with strong oxidants, strong acids or strong bases.

Always consult the specific safety data sheet and relevant literature before using the compound, and follow reasonable safety instructions.

Last Update：2024-04-09 21:54:55