4-Chloro-3-(trifluoromethyl)pyridine

4-Chloro-3-(trifluoromethyl)pyridine - Names and Identifiers

Name	4-Chloro-3-(trifluoromethyl)pyridine
Synonyms	SKL338 4-trifluoromethyl-3-chloropyridine 3-chloro-4-trifluoromethyl pyridine 3-chloro-4-(trifluoromethyl)yridine 4-Chloro-3-(trifluoromethyl)pyridine 3-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE Pyridine, 3-chloro-4-(trifluoromethyl)-
CAS	81565-19-7

4-Chloro-3-(trifluoromethyl)pyridine - Physico-chemical Properties

Molecular Formula	C6H3ClF3N
Molar Mass	181.54
Density	1.407 g/cm3
Melting Point	-23--20 °C
Boling Point	142-144 °C
pKa	0.59±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

4-Chloro-3-(trifluoromethyl)pyridine - Risk and Safety

Risk Codes	R11 - Highly Flammable R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S16 - Keep away from sources of ignition. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

4-Chloro-3-(trifluoromethyl)pyridine - Introduction

4-Chloro-3-(trifluoromethyl)pyridine is an organic compound with the chemical formula C6H3ClF3N. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 4-Chloro-3-(trifluoromethyl)pyridine is a colorless to yellow liquid.
-Melting point:-18 ℃
-Boiling point: 106-108 ℃
-Density: 1.487g/cm³
-Stability: It is stable under conventional conditions, but can react violently with strong oxidants.

Use:
4-Chloro-3-(trifluoromethyl)pyridine have some of the following primary uses:
-Chemical reagent: It can be used as a reagent and raw material in organic synthesis, and used to synthesize other organic compounds, such as drugs and pesticides.
-Pesticide: It can be used as an intermediate of pesticides and used to synthesize pesticides and herbicides and other pesticide products.
-Pharmaceutical field: In drug research and development, 4-Chloro-3-(trifluoromethyl)pyridine is also used as an intermediate.

Preparation Method:
The preparation of 4-Chloro-3-(trifluoromethyl)pyridine is generally carried out by the following reaction:
1. Pyridine is reacted with trifluoroformic acid to obtain 3-(trifluoromethyl) pyridine.
2. Reaction of 3-(trifluoromethyl)pyridine with hydrogen chloride gives 4-Chloro-3-(trifluoromethyl)pyridine.

Safety Information:
When using and handling 4-Chloro-3-(trifluoromethyl)pyridine, pay attention to the following safety precautions:
- 4-Chloro-3-(trifluoromethyl)pyridine is irritating and can cause eye, skin and respiratory tract irritation. Appropriate personal protective equipment, such as gloves, safety glasses and protective face shields, should be worn during operation.
-It should be kept in a closed container and away from heat, open flames and oxidants.
-When handling and handling 4-Chloro-3-(trifluoromethyl)pyridine, please follow the correct laboratory operating procedures and safety operating guidelines.

Last Update：2024-04-09 19:05:52