4-Chloro-3-Hydroxy-Pyridine - Names and Identifiers
4-Chloro-3-Hydroxy-Pyridine - Physico-chemical Properties
Molecular Formula | C5H4ClNO
|
Molar Mass | 129.54 |
Density | 1.392±0.06 g/cm3(Predicted) |
Boling Point | 298.2±20.0 °C(Predicted) |
Flash Point | 134.1°C |
Vapor Presure | 0.000727mmHg at 25°C |
pKa | 6.57±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.583 |
4-Chloro-3-Hydroxy-Pyridine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R41 - Risk of serious damage to eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
4-Chloro-3-Hydroxy-Pyridine - Introduction
It is an organic compound with the chemical formula C5H4ClNO. The following is a description of its nature, use, formulation and safety information:
Nature:
is a white solid with a special smell. It has a melting point of about 60-62°C and a boiling point of about 216-218°C. It is insoluble in water, but soluble in organic solvents such as ethanol and chloroform.
Use:
It is an important organic synthesis intermediate, which is widely used in the fields of medicine, pesticide and dye. It can be used in the preparation of a variety of drugs, such as the treatment of depression drug Propystone (Bupropion); can also be used in the synthesis of pesticides and insecticides.
Preparation Method:
The preparation of calcium can be obtained by the reaction of 3-hydroxypyridine with thionyl chloride. For specific synthetic steps, reference may be made to the organic synthesis literature.
Safety Information:
In general, it is a low-toxic compound, but it is still necessary to pay attention to safe operation. Avoid touching the skin and inhaling dust during use and storage. Use should wear protective gloves and masks to ensure safety. In case of contact or inhalation, rinse immediately with clean water and seek medical attention.
Please note that when conducting chemical experiments or using organic compounds, ensure that relevant safe operating procedures and laboratory guidelines are understood and followed.
Last Update:2024-04-09 15:18:01