4-Chloro-3-methoxybenzeneboronicacid

4-Chloro-3-methoxybenzeneboronicacid - Names and Identifiers

Name	(4-Chloro-3-methoxyphenyl)boronic acid
Synonyms	4-chloro-3-methoxyphenylboronic acid 4-Chloro-3-methoxybenzeneboronicacid (4-Chloro-3-methoxyphenyl)boronic acid Boronic acid, (4-chloro-3-Methoxyphenyl)- B-(4-Chloro-3-methoxy-phenyl)boronic acid Boronic acid, B-(4-chloro-3-methoxyphenyl)- boronic acid, B-(4-chloro-3-methoxyphenyl)- 4-Chloro-3-methoxyphenylboronic Acid (contains varyi 4-Chloro-3-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
CAS	89694-47-3
InChI	InChI=1/C7H8BClO3/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,10-11H,1H3

4-Chloro-3-methoxybenzeneboronicacid - Physico-chemical Properties

Molecular Formula	C7H8BClO3
Molar Mass	186.4
Density	1.32±0.1 g/cm3(Predicted)
Melting Point	151°C(lit.)
Boling Point	341.7±52.0 °C(Predicted)
Flash Point	160.425°C
Solubility	soluble in Methanol
Vapor Presure	0mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
pKa	7.91±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.545

4-Chloro-3-methoxybenzeneboronicacid - Introduction

(4-Chloro-3-methoxyphenyl)boronic acid is an organic compound with the chemical formula C7H8BClO3.

Nature:
-Appearance: White crystalline solid
-Melting point: 135-138°C
-solubility: slightly soluble in water, soluble in organic solvents such as ethanol, dimethyl ether

Use:
-Organic synthesis intermediates: Commonly used in organic synthesis as a source of anionic boron reagents, it can react with some organic compounds to generate the corresponding boronic acid derivatives.
-Medical field: The compound is also used in medical research, for example, as a functional group of drug molecules.

Preparation Method:
(4-Chloro-3-methoxyphenyl)boronic acid can be prepared by the following steps:
1.3-Methoxybenzene boronic acid reacts with phosgene to generate oxidized benzene borate in the presence of a base.
2. reacting benzoborate oxide with cadmium chloride to obtain (4-Chloro-3-methoxyphenyl)boronic acid.

Safety Information:
Since there is no special safety information report, it can be assumed that (4-Chloro-3-methoxyphenyl)boronic acid has relatively low toxicity. However, it is still recommended to take appropriate protective measures during operation, such as wearing gloves, glasses and protective clothing. In addition, direct contact with skin and eyes should be avoided and kept away from ignition sources and strong oxidants. If ingested or inhaled, seek medical attention as soon as possible.

Last Update：2024-04-09 21:04:16