4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine
4-chloro-N-(4-fluorophenyl)-5,6-dimethyl-2-Pyrimidinamine
CAS: 199463-20-2
Molecular Formula: C12H11ClFN3
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine - Names and Identifiers
| Name | 4-chloro-N-(4-fluorophenyl)-5,6-dimethyl-2-Pyrimidinamine |
| Synonyms | 4-Chloro-2-(4-fluorophenylamino)-5,6-dimethylpyrimidine 4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine 4-chloro-N-(4-fluorophenyl)-5,6-dimethyl-2-Pyrimidinamine 4-Chloro-N-(4-fluorophenyl)-5,6-diMethylpyriMidin-2-aMine 2-Pyrimidinamine, 4-chloro-N-(4-fluorophenyl)-5,6-dimethyl- |
| CAS | 199463-20-2 |
| InChI | InChI=1S/C12H11ClFN3/c1-7-8(2)15-12(17-11(7)13)16-10-5-3-9(14)4-6-10/h3-6H,1-2H3,(H,15,16,17) |
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine - Physico-chemical Properties
| Molecular Formula | C12H11ClFN3 |
| Molar Mass | 251.69 |
| Density | 1.320±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 398.7±52.0 °C(Predicted) |
| pKa | 3.86±0.10(Predicted) |
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine - Introduction
4-chloro-N-(4-fluorophenyl)-5, also known as 4-Chloro-2-(4-fluoroanilino)-5,6-dimethylpyrimidine, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4-chloro-N-(4-fluorophenyl)-5, which is white to light yellow crystal.
-Solubility: It is soluble in organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane at room temperature, but insoluble in water.
Use:
-Chemical synthesis: 4-chloro-N-(4-fluorophenyl)-5, is an important intermediate compound, which is widely used in drug synthesis and other organic synthesis. It can be used as a precursor of certain drugs and can also be used to prepare biologically active compounds.
-Drug research: Due to the special properties of its structure, it can be used to develop new drugs in drug research.
Method:
4-chloro-N-(4-fluorophenyl)-5, which can be synthesized by the following steps:
1.4-chloro -5,6-dimethyl pyrimidine reacts with sodium cyanide to generate the corresponding sodium salt.
2. React sodium cyanide salt with 4-fluoroaniline to generate 4-chloro-N-(4-fluorophenyl)-5.
Safety Information:
- 4-chloro-N-(4-fluorophenyl)-5, you should avoid contact with strong oxidants during use and storage to prevent dangerous reactions.
-When in contact with skin, eyes or respiratory tract due to its irritation, rinse immediately with plenty of water and seek medical help.
-Store the compound in a dry, ventilated place away from sources of ignition.
Nature:
-Appearance: 4-chloro-N-(4-fluorophenyl)-5, which is white to light yellow crystal.
-Solubility: It is soluble in organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane at room temperature, but insoluble in water.
Use:
-Chemical synthesis: 4-chloro-N-(4-fluorophenyl)-5, is an important intermediate compound, which is widely used in drug synthesis and other organic synthesis. It can be used as a precursor of certain drugs and can also be used to prepare biologically active compounds.
-Drug research: Due to the special properties of its structure, it can be used to develop new drugs in drug research.
Method:
4-chloro-N-(4-fluorophenyl)-5, which can be synthesized by the following steps:
1.4-chloro -5,6-dimethyl pyrimidine reacts with sodium cyanide to generate the corresponding sodium salt.
2. React sodium cyanide salt with 4-fluoroaniline to generate 4-chloro-N-(4-fluorophenyl)-5.
Safety Information:
- 4-chloro-N-(4-fluorophenyl)-5, you should avoid contact with strong oxidants during use and storage to prevent dangerous reactions.
-When in contact with skin, eyes or respiratory tract due to its irritation, rinse immediately with plenty of water and seek medical help.
-Store the compound in a dry, ventilated place away from sources of ignition.
Last Update：2024-04-09 15:17:54
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Product Name: 4-chloro-N-(4-fluorophenyl)-5,6-dimethyl-2-Pyrimidinamine Request for quotationCAS: 199463-20-2
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Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine Visit Supplier Webpage Request for quotation
CAS: 199463-20-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 199463-20-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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