4-Chloro-5,7-difluoroquinoline

4-Chloro-5,7-difluoroquinoline - Names and Identifiers

Name	4-Chloro-5,7-difluoroquinoline
Synonyms	4-Chloro-5,7-difluoroquinoline Quinoline, 4-chloro-5,7-difluoro-
CAS	874831-46-6

4-Chloro-5,7-difluoroquinoline - Physico-chemical Properties

Molecular Formula	C9H4ClF2N
Molar Mass	199.587
Density	1.455±0.06 g/cm3(Predicted)
Boling Point	256.9±35.0 °C(Predicted)
pKa	1.42±0.39(Predicted)

4-Chloro-5,7-difluoroquinoline - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

4-Chloro-5,7-difluoroquinoline - Introduction

4-Chloro-5,7-difluoroquinoline(4-Chloro-5,7-difluoroquinoline) is an organic compound. Its chemical formula is C9H4ClF2N, and has the following properties and applications.

Nature:
1. Appearance: 4-Chloro-5,7-difluoroquinoline is a colorless or light yellow solid substance.
2. Melting Point: its melting point is about 61-63 degrees Celsius.
3. Boiling point: Its boiling point is about 310 degrees Celsius.
4. Solubility: It is slightly soluble in water, but easily soluble in organic solvents, such as Alcohols, Ketones and esters.
5. Chemical activity: 4-Chloro-5,7-difluoroquinoline is an aromatic compound with strong electron affinity and can participate in organic synthesis reactions.

Use:
1. Pharmaceutical field: 4-Chloro-5,7-difluoroquinoline can be used as drug intermediates for the synthesis of some biologically active compounds, such as anti-tumor drugs, antiviral drugs.
2. Agricultural field: It can also be used as a pesticide intermediate for the synthesis of some effective pesticides and fungicides.
3. Scientific Research Field: Due to its chemical activity and special structure, 4-Chloro-5,7-difluoroquinoline can also be used in organic synthesis, drug discovery and biological activity research in scientific research.

Method:
4-Chloro-5,7-difluoroquinoline has many preparation methods, and the commonly used methods include the following:
1. React 5,7-difluoroquinoline with chlorine to generate 4-Chloro-5,7-difluoroquinoline.
2. The functional groups of chlorine and fluorine are introduced into the quinoline compound, and 4-Chloro-5,7-difluoroquinoline is obtained after necessary reaction steps.

Safety Information:
When using 4-Chloro-5,7-difluoroquinoline, you need to pay attention to its safety:
1. Should wear appropriate protective equipment, such as chemical goggles, protective gloves, etc.
2. Avoid inhalation of dust or vapor, use should maintain good ventilation.
3. Avoid contact with the skin, such as contact with skin should immediately rinse with plenty of water.
4. Keep away from fire and oxidant, avoid high temperature and direct sunlight.
5. Please keep it properly and keep it away from children.
6. In the use or handling of this material, should comply with the relevant safety procedures.

Last Update：2024-04-09 19:05:54