4-Chloro-5-nitropyridine-2-aMine
2-Pyridinamine, 4-chloro-5-nitro-
CAS: 24484-96-6
Molecular Formula: C5H4ClN3O2
4-Chloro-5-nitropyridine-2-aMine - Names and Identifiers
| Name | 2-Pyridinamine, 4-chloro-5-nitro- |
| Synonyms | 2-AMino-4-chloro-5-nitrop... 4-Chloro-5-nitropyridin-2-amine 4-Chloro-5-nitro-2-pyridinaMine 2-AMINO-4-CHLORO-5-NITROPYRIDINE 6-Amino-4-chloro-3-nitropyridine 4-Chloro-5-nitropyridine-2-aMine 2-Pyridinamine, 4-chloro-5-nitro- 2-pyridinamine, 4-chloro-5-nitro- 4-CHLORO-5-NITRO-PYRIDIN-2-YLAMINE |
| CAS | 24484-96-6 |
| InChI | InChI=1/C5H4ClN3O2/c6-3-1-5(7)8-2-4(3)9(10)11/h1-2H,(H2,7,8) |
4-Chloro-5-nitropyridine-2-aMine - Physico-chemical Properties
| Molecular Formula | C5H4ClN3O2 |
| Molar Mass | 173.56 |
| Density | 1.596 |
| Melting Point | 240-242°C |
| Boling Point | 377℃ |
| Flash Point | 182℃ |
| Solubility | DMF, DMSO, Hot Ethanol, Ethyl Acetate, Hot Methanol |
| Vapor Presure | 6.85E-06mmHg at 25°C |
| Appearance | Solid |
| Color | Brown |
| pKa | 1.77±0.24(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.657 |
4-Chloro-5-nitropyridine-2-aMine - Introduction
2-Pyridinamine, 4-chroo-5-nitro-is an organic compound with the chemical formula C5H4ClN3O2. It is a yellow crystalline powder, stable at room temperature.
Nature:
-Appearance: Yellow crystalline powder
-Molecular weight: 173.56g/mol
-Melting point: 112-116 degrees Celsius
-Boiling point: 343.6 degrees Celsius
-insoluble in water, slightly soluble in some organic solvents such as ethanol and ethers.
Use:
2-Pyridinamine, 4-chroo-5-nitro-is commonly used in the fields of pharmaceuticals, dyes and pesticides. It can be used as an organic synthesis intermediate for the synthesis of other compounds, such as the synthesis of barbituric acid. In addition, it can also be used in the manufacture of pesticides and fungicides in agriculture.
Method:
2-Pyridinamine, 4-chloro-5-nitro-synthesis methods are varied, and the common methods are as follows:
-synthesis of open Venturi: 2-aminopyridine is reacted with chlorone (such as 4-chloropentanone) and nitric acid to obtain 2-Pyridinamine, 4-chloroo-5-nitro-.
-Synthesis of diazo compounds: first, 2-aminopyridine reacts with sodium nitrite to generate diazo compounds, and then electrophilic aromatic substitution reaction with cuprous chloride and ammonium chloride to obtain the target product.
Safety Information:
2-Pyridinamine, 4-choro-5-nitro-in general can be regarded as low toxic chemicals, but still need to pay attention to the following safety matters:
-Avoid inhaling dust and avoid contact with skin and eyes.
-Wear appropriate protective equipment such as lab gloves, goggles and protective clothing when in use.
-Store and handle the compound properly, avoiding fire and high temperatures.
-Please maintain a well-ventilated laboratory environment during operation. In the event of an accident, take immediate emergency measures and seek medical help.
Nature:
-Appearance: Yellow crystalline powder
-Molecular weight: 173.56g/mol
-Melting point: 112-116 degrees Celsius
-Boiling point: 343.6 degrees Celsius
-insoluble in water, slightly soluble in some organic solvents such as ethanol and ethers.
Use:
2-Pyridinamine, 4-chroo-5-nitro-is commonly used in the fields of pharmaceuticals, dyes and pesticides. It can be used as an organic synthesis intermediate for the synthesis of other compounds, such as the synthesis of barbituric acid. In addition, it can also be used in the manufacture of pesticides and fungicides in agriculture.
Method:
2-Pyridinamine, 4-chloro-5-nitro-synthesis methods are varied, and the common methods are as follows:
-synthesis of open Venturi: 2-aminopyridine is reacted with chlorone (such as 4-chloropentanone) and nitric acid to obtain 2-Pyridinamine, 4-chloroo-5-nitro-.
-Synthesis of diazo compounds: first, 2-aminopyridine reacts with sodium nitrite to generate diazo compounds, and then electrophilic aromatic substitution reaction with cuprous chloride and ammonium chloride to obtain the target product.
Safety Information:
2-Pyridinamine, 4-choro-5-nitro-in general can be regarded as low toxic chemicals, but still need to pay attention to the following safety matters:
-Avoid inhaling dust and avoid contact with skin and eyes.
-Wear appropriate protective equipment such as lab gloves, goggles and protective clothing when in use.
-Store and handle the compound properly, avoiding fire and high temperatures.
-Please maintain a well-ventilated laboratory environment during operation. In the event of an accident, take immediate emergency measures and seek medical help.
Last Update：2024-04-10 22:29:15
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