4-Chloro-6,7-dimethoxyquinazoline
4-Chloro-6,7-dimethoxyquinazoline
CAS: 13790-39-1
Molecular Formula: C10H9ClN2O2
4-Chloro-6,7-dimethoxyquinazoline - Names and Identifiers
| Name | 4-Chloro-6,7-dimethoxyquinazoline |
| Synonyms | 4-Chloro-6,7-Dimethoxyquinazol 4-Chloro-6,7-dimethoxy-quizoline 4-Chloro-6,7-dimethoxyquinazoline 6,7-dimethoxyquinazolin-4(1H)-one 4-Cholro-6,7-dimethoxyquinazoline 4-CHLORO-6,7-DIMETHOXYQUINAZOLINE 6,7-Dimethoxy-4-Chloro-Quinzaoline Quinazoline, 4-chloro-6,7-dimethoxy- 4-Chloro- 6,7-Dimethoxyquinazoline New |
| CAS | 13790-39-1 |
| EINECS | 672-791-6 |
| InChI | InChI=1/C10H9ClN2O2/c1-14-8-3-6-7(4-9(8)15-2)12-5-13-10(6)11/h3-5H,1-2H3 |
4-Chloro-6,7-dimethoxyquinazoline - Physico-chemical Properties
| Molecular Formula | C10H9ClN2O2 |
| Molar Mass | 224.64 |
| Density | 1.321±0.06 g/cm3(Predicted) |
| Melting Point | 185 °C |
| Boling Point | 345.5±37.0 °C(Predicted) |
| Flash Point | 162.765°C |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Light yellow powder |
| Color | White to Yellow |
| pKa | 0.77±0.30(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.605 |
| MDL | MFCD01570172 |
4-Chloro-6,7-dimethoxyquinazoline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37 - Wear suitable gloves. |
| Hazard Note | Irritant |
4-Chloro-6,7-dimethoxyquinazoline - Reference Information
| Uses | 4-chloro-6, 7-dimethoxyquinazoline is an important intermediate for the synthesis of 4-substituted 6, 7-dimethoxyquinazoline derivatives, 6, 7-dimethoxyquinazoline derivatives are inhibitory to platelet-derived growth factor receptors ( PDGFR), this shows that it can inhibit a variety of cancer cells without damaging normal cells. |
| Synthesis method | 4-chloro-6, 7-dimethoxyquinazoline can be 4, 5-dimethoxy-2-aminobenzoic acid As a raw material, it is obtained through cyclization and chlorination reactions. The synthesis reaction formula is as follows: Figure 4-Synthesis reaction formula of chloro-6, 7-dimethoxyquinazoline |
Last Update：2024-04-10 22:29:15
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Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: 4-Chloro-6,7-dimethoxyquinazoline Visit Supplier Webpage Request for quotationCAS: 13790-39-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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