4-Chloro-6-hydroxy-7-Methoxyquinazoline
6-Quinazolinol, 4-chloro-7-methoxy-
CAS: 574745-97-4
Molecular Formula: C9H7ClN2O2
4-Chloro-6-hydroxy-7-Methoxyquinazoline - Names and Identifiers
| Name | 6-Quinazolinol, 4-chloro-7-methoxy- |
| Synonyms | 4-Chloro-6-hydroxy-7-meth... 4-chloro-7-Methoxyquinazolin-6-ol 6-Quinazolinol, 4-chloro-7-methoxy- 4-Chloro-6-hydroxy-7-Methoxyquinazoline |
| CAS | 574745-97-4 |
4-Chloro-6-hydroxy-7-Methoxyquinazoline - Physico-chemical Properties
| Molecular Formula | C9H7ClN2O2 |
| Molar Mass | 210.62 |
| Density | 1.458±0.06 g/cm3(Predicted) |
| Boling Point | 355.8±37.0 °C(Predicted) |
| pKa | 7.55±0.40(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD12547341 |
4-Chloro-6-hydroxy-7-Methoxyquinazoline - Introduction
6-Quinazolinol, 4-chloro-7-methoxy-, chemical formula is C10H8ClNO2, molecular weight is 215.63. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-melting point: 171-175 ℃
-Solubility: Soluble in ethanol, chloroform and ether, slightly soluble in water
Use:
6-Quinazolinol, 4-choro-7-methoxy-is an organic synthesis intermediate commonly used in the synthesis of drugs and pesticides. It can also be used as an optical dye, solvent and raw material for the synthesis of other organic compounds.
Preparation Method:
6-Quinazolinol, 4-choro-7-methoxy-can be prepared in a variety of ways. The following is a common synthetic route:
1. 4-chloro-2-nitroquinazoline is reacted with methanol to obtain 4-chloro-2-methoxyquinazoline.
2. Under alkaline conditions, 4-chloro-2-methoxyquinazoline is reacted with hydrogen peroxide to obtain 6-Quinazolinol, 4-chloro-7-methoxy-.
Safety Information:
When using and operating 6-Quinazolinol, 4-choro-7-methoxy-, the following safety precautions should be paid attention:
-Wear appropriate personal protective equipment, such as glasses, gloves and masks, due to possible irritation and injury to the eyes, skin and respiratory tract.
-Avoid contact with strong oxidants and fire sources to prevent fire or explosion.
-Use in a well-ventilated place to avoid inhaling its vapors.
-If inhaled or exposed by accident, seek medical help immediately and bring the chemical safety information sheet of the compound to the hospital.
Nature:
-Appearance: White solid
-melting point: 171-175 ℃
-Solubility: Soluble in ethanol, chloroform and ether, slightly soluble in water
Use:
6-Quinazolinol, 4-choro-7-methoxy-is an organic synthesis intermediate commonly used in the synthesis of drugs and pesticides. It can also be used as an optical dye, solvent and raw material for the synthesis of other organic compounds.
Preparation Method:
6-Quinazolinol, 4-choro-7-methoxy-can be prepared in a variety of ways. The following is a common synthetic route:
1. 4-chloro-2-nitroquinazoline is reacted with methanol to obtain 4-chloro-2-methoxyquinazoline.
2. Under alkaline conditions, 4-chloro-2-methoxyquinazoline is reacted with hydrogen peroxide to obtain 6-Quinazolinol, 4-chloro-7-methoxy-.
Safety Information:
When using and operating 6-Quinazolinol, 4-choro-7-methoxy-, the following safety precautions should be paid attention:
-Wear appropriate personal protective equipment, such as glasses, gloves and masks, due to possible irritation and injury to the eyes, skin and respiratory tract.
-Avoid contact with strong oxidants and fire sources to prevent fire or explosion.
-Use in a well-ventilated place to avoid inhaling its vapors.
-If inhaled or exposed by accident, seek medical help immediately and bring the chemical safety information sheet of the compound to the hospital.
Last Update：2024-04-09 15:17:58
