4-Chloro-6-methoxy-quizoline
6-methoxyquinazolin-4-amine
CAS: 50424-28-7;885277-51-0
Molecular Formula: C9H7ClN2O
4-Chloro-6-methoxy-quizoline - Names and Identifiers
| Name | 6-methoxyquinazolin-4-amine |
| Synonyms | 6-methoxyquinazolin-4-amine 4-Chloro-6-methoxy-quizoline 4-Chloro-6-Methoxyquinazo... 4-Quinazolinamine, 6-Methoxy- 6-Methoxy-Quinazolin-4-Ylamine 6-METHOXY-QUINAZOLIN-4-YLAMINE Quinazoline, 4-chloro-6-methoxy- 4-chloro-6-Methoxy-4a,8a-dihydroquinazoline |
| CAS | 50424-28-7 885277-51-0 |
| InChI | InChI=1/C9H9N3O/c1-13-6-2-3-8-7(4-6)9(10)12-5-11-8/h2-5H,1H3,(H2,10,11,12) |
4-Chloro-6-methoxy-quizoline - Physico-chemical Properties
| Molecular Formula | C9H7ClN2O |
| Molar Mass | 194.62 |
| Density | 1.333±0.06 g/cm3(Predicted) |
| Melting Point | 107.5-108 °C |
| Boling Point | 323.0±22.0 °C(Predicted) |
| Flash Point | 174.941°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 0.59±0.30(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.675 |
4-Chloro-6-methoxy-quizoline - Introduction
6-methoxyquinazolin-4-amine is an organic compound whose chemical formula is C10H10N4O.
Nature:
1. Appearance: 6-methoxyquinazolin-4-amine is a white to light yellow crystalline powder.
2. Solubility: It has good solubility in common organic solvents.
3. Melting point: Its melting point range is usually between 180-182°C.
Use:
6-methoxyquinazolin-4-amine has a wide range of applications in the field of medicinal chemistry, including the following aspects:
1. As a drug precursor: It can be used as an intermediate for the synthesis of other drugs, and its biological activity and physicochemical properties can be changed by chemical modification of its structure.
2. Anti-cancer research: It is used to research and develop new anti-cancer drugs because it has the potential to inhibit the growth and spread of tumor cells.
3. Endogenous functional group detection: It can be used as a fluorescent probe for detecting and determining specific biologically active molecules in biological samples.
Preparation Method:
The preparation method of 6-methoxyquinazolin-4-amine can be carried out by the following steps:
1. First, 2,3-diaminopyridine is reacted with 4-chloromethoxyacetophenone to obtain the intermediate 4-chloromethoxypyridine-2, 3-diamine.
2. Then, by reacting with sodium hypochlorite, the methyl ether group in the intermediate is converted into methylamino group to generate 6-methoxyquinazolin-4-amine.
Safety Information:
1. 6-methoxyquinazolin-4-amine is a chemical that must be used under appropriate laboratory conditions to avoid contact with skin, eyes and inhalation.
2. Follow proper laboratory safety procedures, including wearing appropriate protective equipment, such as gloves and goggles.
3. The supplier shall provide the relevant safety data sheet, which contains detailed safety information and operating recommendations for the compound.
Nature:
1. Appearance: 6-methoxyquinazolin-4-amine is a white to light yellow crystalline powder.
2. Solubility: It has good solubility in common organic solvents.
3. Melting point: Its melting point range is usually between 180-182°C.
Use:
6-methoxyquinazolin-4-amine has a wide range of applications in the field of medicinal chemistry, including the following aspects:
1. As a drug precursor: It can be used as an intermediate for the synthesis of other drugs, and its biological activity and physicochemical properties can be changed by chemical modification of its structure.
2. Anti-cancer research: It is used to research and develop new anti-cancer drugs because it has the potential to inhibit the growth and spread of tumor cells.
3. Endogenous functional group detection: It can be used as a fluorescent probe for detecting and determining specific biologically active molecules in biological samples.
Preparation Method:
The preparation method of 6-methoxyquinazolin-4-amine can be carried out by the following steps:
1. First, 2,3-diaminopyridine is reacted with 4-chloromethoxyacetophenone to obtain the intermediate 4-chloromethoxypyridine-2, 3-diamine.
2. Then, by reacting with sodium hypochlorite, the methyl ether group in the intermediate is converted into methylamino group to generate 6-methoxyquinazolin-4-amine.
Safety Information:
1. 6-methoxyquinazolin-4-amine is a chemical that must be used under appropriate laboratory conditions to avoid contact with skin, eyes and inhalation.
2. Follow proper laboratory safety procedures, including wearing appropriate protective equipment, such as gloves and goggles.
3. The supplier shall provide the relevant safety data sheet, which contains detailed safety information and operating recommendations for the compound.
Last Update：2024-04-09 21:01:54
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Spot supply
Product Name: ???4-Chloro-6-methoxyquinazoline Visit Supplier Webpage Request for quotationCAS: 50424-28-7
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 4-Chloro-6-methoxyquinazoline Visit Supplier Webpage Request for quotationCAS: 50424-28-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-Chloro-6-methoxyquinazoline Visit Supplier Webpage Request for quotationCAS: 50424-28-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple Specifications
Product Name: 6-METHOXY-QUINAZOLIN-4-YLAMINE Visit Supplier Webpage Request for quotationCAS: 50424-28-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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