4-Chloroindole-2,3-dione - Names and Identifiers
Name | 4-Chloroisatin
|
Synonyms | 4-CHLOROISATIN 4-Chloroisatin 4-Chloroindole-2,3-dione 4-CHLOROINDOLE-2,3-DIONE 4-CHLORO-2,3-INDOLINEDIONE Indole-2,3-dione, 4-chloro- 4-chloro-1H-indole-2,3-dione 4-Chloro-(1H)-indole-2,3-dione 4-Chloro-2,3-dihydro-1H-indole-2,3-dione 4-Chloroindole-2,3-dione4-Chloro-2,3-indolinedione
|
CAS | 6344-05-4
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EINECS | 1533716-785-6 |
InChI | InChI=1/C8H4ClNO2/c9-4-2-1-3-5-6(4)7(11)8(12)10-5/h1-3H,(H,10,11,12) |
4-Chloroindole-2,3-dione - Physico-chemical Properties
Molecular Formula | C8H4ClNO2
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Molar Mass | 181.58 |
Density | 1.519±0.06 g/cm3(Predicted) |
Melting Point | 258 °C |
Solubility | soluble in Dimethylformamide |
Appearance | Solid |
Color | Light yellow to Brown |
pKa | 9.44±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.626 |
MDL | MFCD00129178 |
4-Chloroindole-2,3-dione - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Class | IRRITANT |
4-Chloroindole-2,3-dione - Introduction
4-Chloroisatin is an organic compound with a chemical formula of C8H4ClNO2 and a molecular weight of 175.58g/mol. It is a red to blue crystalline solid, soluble in organic solvents such as alcohols and ethers, and practically insoluble in water.
4-Chloroisatin is widely used in biomedical research as a dye and indicator. It is used for fluorescent staining in cell culture and can be used to observe cell morphology and physiological processes. In addition, it is also commonly used in protein electrophoresis as a stain, which can be used to detect and analyze the migration and concentration of proteins.
In the preparation method, 4-Chloroisatin can be obtained by chlorinating isatin. First, isatin is reacted with a chlorinating agent such as chlorine gas or chlorous acid, and chlorination is carried out under appropriate conditions to produce 4-Chloroisatin.
Pay attention to safety when using and handling 4-Chloroisatin. It is a toxic compound that can cause irritation and damage to the skin, eyes and respiratory system. Therefore, personal protective equipment such as gloves, safety glasses and protective masks should be worn during handling and contact. At the same time, it should be stored in a dry, sealed place away from heat and fire sources, and avoid contact with flammable materials. Local environmental and safety measures should be followed when disposing of waste. Follow the relevant laboratory safety instructions.
Last Update:2024-04-10 22:29:15