4-Cyanobenzene-1-Sulfonamide

4-Cyanobenzene-1-Sulfonamide - Names and Identifiers

Name	p-Cyanobenzenesulphonamide
Synonyms	NSC 77086 BRN 2093857 4-Sulphamoylbenzonitrile 4-cyanobenzenesulfonamide p-Cyanobenzenesulfonamide p-cyano-benzenesulfonamid 4-CYANOBENZENESULFONAMIDE p-Cyanobenzenesulphonamide Benzenesulfonamide, 4-cyano- 4-Cyanobenzene-1-Sulfonamide Benzenesulfonamide, p-cyano- 4-CYANOBENZENE-1-SULFONAMIDE 4-CYANOBENZENE-1-SULPHONAMIDE 4-11-00-00694 (Beilstein Handbook Reference) 4-Sulphamoylbenzonitrile, 4-(Aminosulphonyl)benzonitrile
CAS	3119-02-6
EINECS	221-492-5
InChI	InChI=1/C7H6N2O2S/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,(H2,9,10,11)

4-Cyanobenzene-1-Sulfonamide - Physico-chemical Properties

Molecular Formula	C7H6N2O2S
Molar Mass	182.2
Density	1.3827 (rough estimate)
Melting Point	166 °C
Boling Point	400.7±47.0 °C(Predicted)
Flash Point	196.2°C
Water Solubility	1.111g/L(15 ºC)
Vapor Presure	1.24E-06mmHg at 25°C
pKa	9.57±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.6000 (estimate)

4-Cyanobenzene-1-Sulfonamide - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves.
UN IDs	3276
RTECS	DB1582000
HS Code	29350090
Hazard Note	Harmful
Hazard Class	IRRITANT

4-Cyanobenzene-1-Sulfonamide - Introduction

p-Cyanobenzenesulphonamide, also known as p-Cyanobenzenesulphonamide, is an organic compound. The following is a description of its nature, use, preparation and safety information:

1. Nature:
-Appearance: White crystalline solid
-Molecular formula: C7H6N2O2S
-Molecular weight: 186.20g/mol
-Melting point: 142-144 ° C
-Boiling point: 387.5 ° C (predicted value)
-Density: 1.45 g/mL
-Insoluble in water, but soluble in organic solvents such as ethanol and dimethyl sulfoxide.

2. Use:
- p-Cyanobenzenesulphonamide is a commonly used organic synthesis intermediate that can be used to synthesize other compounds.
-It has applications in the field of medicine and can be used to synthesize certain drugs, dyes and pigments.

3. Preparation method:
-It can be prepared by reacting p-nitrobenzene sulfonyl chloride (p-Nitrobenzenesulfonyl chloride) with sodium cyanide. First, under appropriate reaction conditions, nitrobenzenesulfonyl chloride reacts with sodium cyanide to produce Cyanobenzenesulfonyl chloride (Cyanobenzenesulfonyl chloride), and then the resulting product is reduced and hydrolyzed to obtain p-Cyanobenzenesulphonamide.

4. Safety Information:
- p-Cyanobenzenesulphonamide is relatively stable under regular operating conditions, but it may be toxic, irritating, and may cause health hazards.
-During use or storage, care should be taken to prevent inhalation, contact with skin, entry into eyes or ingestion. Wear appropriate protective equipment, such as gloves, safety glasses and face masks, if necessary.
-In the operation should pay attention to the use of appropriate ventilation system, to avoid a large amount of dust. If accidentally splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help.
-Before the synthesis or use of the compound, it is necessary to understand and follow the relevant safety procedures and regulations in detail to ensure the safety of the working environment.

Last Update：2024-04-09 15:17:56